Computational analysis of the silver nanoparticle–human serum albumin complex

Z Hazarika, AN Jha - ACS omega, 2019 - ACS Publications
Drug delivery in excess concentrations and at not-specified sites inside the human body
adversely affects the body and gives rise to other diseases. Several methods have been …

Amphiphilic drug–additive systems in aqueous and organic solvent–water mixed media: A comprehensive account on physicochemical properties

J Gurung, J Anjudikkal, AK Pulikkal - Journal of Molecular Liquids, 2020 - Elsevier
The physicochemical properties of drugs and drug–additive interactions have great
importance to elucidate the pharmacological effect of the drug formulations. Plentiful …

The interplay between non-esterified fatty acids and plasma zinc and its influence on thrombotic risk in obesity and type 2 diabetes

SJ Hierons, JS Marsh, D Wu, CA Blindauer… - International journal of …, 2021 - mdpi.com
Thrombosis is a major comorbidity of obesity and type-2 diabetes mellitus (T2DM). Despite
the development of numerous effective treatments and preventative strategies to address …

Studies on conformational changes induced by binding of pendimethalin with human serum albumin

MI Ahmad, AM Potshangbam, M Javed, M Ahmad - Chemosphere, 2020 - Elsevier
Abstracts Pendimethalin (PND) is a widely used herbicide in modern means of agricultural
practices. So, its toxic residues exist extensively in the environment and can enter human …

Molecular interaction of di-ester bonded cationic Gemini surfactants with pepsin: in vitro and in silico perspectives

M Akram, M Osama, MA Hashmi… - Journal of Biomolecular …, 2023 - Taylor & Francis
The implications of surfactant–enzyme/protein interactions in a variety of fields, including
biotechnology, cosmetics, paints and pharmaceuticals, have attracted a lot of attention in …

Plasma protein binding of herbal-flavonoids to human serum albumin and their anti-proliferative activities

IH Gecibesler, M Aydin - Anais da Academia Brasileira de Ciências, 2020 - SciELO Brasil
Herbal-flavonoids (HF) as polyphenolic secondary metabolites are taken in the daily diet to
join in many metabolic processes in the human organism. Anti-proliferative activities and …

Small Angle Neutron Scattering in Drug Discovery Research: A Novel Tool for Advanced Study of Structures of Biological Macromolecules

L Adhikari, H Mishra, M Semalty… - Current Drug Discovery …, 2023 - ingentaconnect.com
Small Angle Neutron Scattering (SANS) is a powerful and novel tool for the study of soft
condensed matter, including the microscopic and nanomaterials used for drug discovery …

Characterization of interactions of montelukast sodium with human serum albumin: multi-spectroscopic techniques and computer simulation studies

S Zheng, X Fang, F Li, Q Sun, M Zhao, H Wei… - New Journal of …, 2022 - pubs.rsc.org
Montelukast sodium (MLS) is a leukotriene receptor antagonist that is widely used to treat
asthma in clinical treatment. To further understand the pharmacological mechanism of MLS …

Spectroscopic investigations of the interactions of potential antitumor amino-thiazolidinone platinum (II) compounds with human serum albumin

J Shao, JX Wei, Y Zhang, JY Xu - Inorganic Chemistry Communications, 2019 - Elsevier
An amino-thiazolidinone platinum (II) compound which could rapidly induce apoptosis in
tumor cells and showed no cross resistance against the cisplatin-resistant cells, was firstly to …

[HTML][HTML] 典型生物碱与血清蛋白相互作用CE 分析方法比较与理论建模研究

夏琪涵, 郭明, 侯平, 顾奕, 赵富荣 - 药学学报, 2019 - html.rhhz.net
利用毛细管电泳技术建立咖啡因(caffeine) 和人血清白蛋白(HSA) 相互作用的分析方法.
在生理条件下建立配体-受体相互作用模型(caffeine-HSA), 通过前沿分析(frontal-analysis, FA) …