Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum
enables their sequestration via attachment to the microvasculature. This artificially increases …

A distinctive feature of Plasmodium vivax infections is the overall low parasite density in
peripheral blood. Thus, identifying asymptomatic infected individuals in endemic …

Background A very large biomass of intact asexual-stage malaria parasites accumulates in
the spleen of asymptomatic human individuals infected with Plasmodium vivax. The …

Background As malaria endemic countries shift from control to elimination, the proportion of
low density Plasmodium falciparum infections increases. Current field diagnostic tools, such …

Abstract Background Greater Mekong Subregion countries are committed to eliminating
Plasmodium falciparum malaria by 2025. Current elimination interventions target infections …

Introduction Malaria continues to be a major global health problem, with over 228 million
cases and 405,000 deaths estimated to occur annually. Rapid and accurate diagnosis of …

Submicroscopic Plasmodium infections are an important parasite reservoir, but their clinical
relevance is poorly defined. A cross-sectional household survey was conducted in southern …

18S rRNA is a biomarker that provides an alternative to thick blood smears in controlled
human malaria infection (CHMI) trials. We reviewed data from CHMI trials at non-endemic …

Plasmodium falciparum infections presenting either as symptomatic or asymptomatic may
contain sexual stage parasites (gametocytes) that are crucial to malaria transmission. In this …

Background Malaria can be transmitted by blood transfusion from human to human and it is
responsible for the majority of transfusion-transmitted infectious diseases worldwide. In sub …