Idiopathic pulmonary fibrosis and lung cancer: mechanisms and molecular targets

B Ballester, J Milara, J Cortijo - International journal of molecular sciences, 2019 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pulmonary
disease with a median survival of 2–4 years after diagnosis. A significant number of IPF …

Epidemiology and risk factors for kidney cancer

WH Chow, LM Dong, SS Devesa - Nature Reviews Urology, 2010 - nature.com
After more than two decades of rising rates, in recent years the total kidney cancer incidence
worldwide has shown signs of stabilizing, or even decreasing. In adults, kidney cancer …

Telomeres, lifestyle, cancer, and aging

MA Shammas - Current Opinion in Clinical Nutrition & Metabolic …, 2011 - journals.lww.com
Telomere length shortens with age. Progressive shortening of telomeres leads to
senescence, apoptosis, or oncogenic transformation of somatic cells, affecting the health …

Effect of Freeze‐Drying on Apple Pomace and Pomegranate Peel Powders Used as a Source of Bioactive Ingredients for the Development of Functional Yogurt

M Ahmed, A Ali, A Sarfraz, Q Hong… - Journal of Food …, 2022 - Wiley Online Library
Agro‐industrial by‐products of fruits have turned into an essential source of bioactive
products. This study examined the effect of freeze‐drying on apple pomace powder (APP) …

Peripheral blood leukocyte telomere length and mortality among 64 637 individuals from the general population

L Rode, BG Nordestgaard… - Journal of the National …, 2015 - academic.oup.com
Background: Short telomeres in peripheral blood leukocytes are associated with older age
and age-related diseases. We tested the hypotheses that short telomeres are associated …

The association of telomere length and cancer: a meta-analysis

IM Wentzensen, L Mirabello, RM Pfeiffer… - … , Biomarkers & Prevention, 2011 - AACR
Background: Telomeres shorten with each cell division and are essential for chromosomal
stability. Short telomeres in surrogate tissues (eg, blood cells) are associated with increased …

Telomeres and early-life stress: an overview

LH Price, HT Kao, DE Burgers, LL Carpenter… - Biological …, 2013 - Elsevier
The long-term sequelae of adverse early-life experiences have long been a focus in
psychiatry, with a historic neurobiological emphasis on physiological systems that are …

How stem cells age and why this makes us grow old

NE Sharpless, RA DePinho - Nature reviews Molecular cell biology, 2007 - nature.com
Recent data suggest that we age, in part, because our self-renewing stem cells grow old as
a result of heritable intrinsic events, such as DNA damage, as well as extrinsic forces, such …

Telomere length and risk of incident cancer and cancer mortality

P Willeit, J Willeit, A Mayr, S Weger, F Oberhollenzer… - Jama, 2010 - jamanetwork.com
Context Telomeres are essential to preserve the integrity of the genome. Critically short
telomeres lead to replicative cell senescence and chromosomal instability and may thereby …

Shortened telomere length is associated with increased risk of cancer: a meta-analysis

H Ma, Z Zhou, S Wei, Z Liu, KA Pooley, AM Dunning… - PloS one, 2011 - journals.plos.org
Background Telomeres play a key role in the maintenance of chromosome integrity and
stability, and telomere shortening is involved in initiation and progression of malignancies. A …