Idiopathic pulmonary fibrosis and lung cancer: mechanisms and molecular targets
B Ballester, J Milara, J Cortijo - International journal of molecular sciences, 2019 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pulmonary
disease with a median survival of 2–4 years after diagnosis. A significant number of IPF …
disease with a median survival of 2–4 years after diagnosis. A significant number of IPF …
Epidemiology and risk factors for kidney cancer
WH Chow, LM Dong, SS Devesa - Nature Reviews Urology, 2010 - nature.com
After more than two decades of rising rates, in recent years the total kidney cancer incidence
worldwide has shown signs of stabilizing, or even decreasing. In adults, kidney cancer …
worldwide has shown signs of stabilizing, or even decreasing. In adults, kidney cancer …
Telomeres, lifestyle, cancer, and aging
MA Shammas - Current Opinion in Clinical Nutrition & Metabolic …, 2011 - journals.lww.com
Telomere length shortens with age. Progressive shortening of telomeres leads to
senescence, apoptosis, or oncogenic transformation of somatic cells, affecting the health …
senescence, apoptosis, or oncogenic transformation of somatic cells, affecting the health …
Effect of Freeze‐Drying on Apple Pomace and Pomegranate Peel Powders Used as a Source of Bioactive Ingredients for the Development of Functional Yogurt
Agro‐industrial by‐products of fruits have turned into an essential source of bioactive
products. This study examined the effect of freeze‐drying on apple pomace powder (APP) …
products. This study examined the effect of freeze‐drying on apple pomace powder (APP) …
Peripheral blood leukocyte telomere length and mortality among 64 637 individuals from the general population
L Rode, BG Nordestgaard… - Journal of the National …, 2015 - academic.oup.com
Background: Short telomeres in peripheral blood leukocytes are associated with older age
and age-related diseases. We tested the hypotheses that short telomeres are associated …
and age-related diseases. We tested the hypotheses that short telomeres are associated …
The association of telomere length and cancer: a meta-analysis
IM Wentzensen, L Mirabello, RM Pfeiffer… - … , Biomarkers & Prevention, 2011 - AACR
Background: Telomeres shorten with each cell division and are essential for chromosomal
stability. Short telomeres in surrogate tissues (eg, blood cells) are associated with increased …
stability. Short telomeres in surrogate tissues (eg, blood cells) are associated with increased …
Telomeres and early-life stress: an overview
LH Price, HT Kao, DE Burgers, LL Carpenter… - Biological …, 2013 - Elsevier
The long-term sequelae of adverse early-life experiences have long been a focus in
psychiatry, with a historic neurobiological emphasis on physiological systems that are …
psychiatry, with a historic neurobiological emphasis on physiological systems that are …
How stem cells age and why this makes us grow old
NE Sharpless, RA DePinho - Nature reviews Molecular cell biology, 2007 - nature.com
Recent data suggest that we age, in part, because our self-renewing stem cells grow old as
a result of heritable intrinsic events, such as DNA damage, as well as extrinsic forces, such …
a result of heritable intrinsic events, such as DNA damage, as well as extrinsic forces, such …
Telomere length and risk of incident cancer and cancer mortality
P Willeit, J Willeit, A Mayr, S Weger, F Oberhollenzer… - Jama, 2010 - jamanetwork.com
Context Telomeres are essential to preserve the integrity of the genome. Critically short
telomeres lead to replicative cell senescence and chromosomal instability and may thereby …
telomeres lead to replicative cell senescence and chromosomal instability and may thereby …
Shortened telomere length is associated with increased risk of cancer: a meta-analysis
H Ma, Z Zhou, S Wei, Z Liu, KA Pooley, AM Dunning… - PloS one, 2011 - journals.plos.org
Background Telomeres play a key role in the maintenance of chromosome integrity and
stability, and telomere shortening is involved in initiation and progression of malignancies. A …
stability, and telomere shortening is involved in initiation and progression of malignancies. A …