An updated overview of diabetic nephropathy: Diagnosis, prognosis, treatment goals and latest guidelines

NM Selby, MW Taal - Diabetes, Obesity and Metabolism, 2020 - Wiley Online Library
Diabetic nephropathy (DN) is a major healthcare challenge. It occurs in up to 50% of those
living with diabetes, is a major cause of end‐stage kidney disease (ESKD) that requires …

Advances in drug delivery-based therapeutic strategies for renal fibrosis treatment

S Huang, H Lu, J Chen, C Jiang, G Jiang… - Journal of Materials …, 2024 - pubs.rsc.org
Renal fibrosis is the result of all chronic kidney diseases and is becoming a major global
health hazard. Currently, traditional treatments for renal fibrosis are difficult to meet clinical …

[HTML][HTML] The systemic nature of CKD

C Zoccali, R Vanholder, ZA Massy, A Ortiz… - Nature Reviews …, 2017 - nature.com
The accurate definition and staging of chronic kidney disease (CKD) is one of the major
achievements of modern nephrology. Intensive research is now being undertaken to unravel …

Evolving importance of kidney disease: from subspecialty to global health burden

KU Eckardt, J Coresh, O Devuyst, RJ Johnson… - The Lancet, 2013 - thelancet.com
In the past decade, kidney disease diagnosed with objective measures of kidney damage
and function has been recognised as a major public health burden. The population …

[HTML][HTML] Impact of Mediterranean diet on metabolic syndrome, cancer and longevity

N Di Daniele, A Noce, MF Vidiri, E Moriconi… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Obesity symbolizes a major public health problem. Overweight and obesity are associated to
the occurrence of the metabolic syndrome and to adipose tissue dysfunction. The adipose …

[HTML][HTML] Summary of KDIGO 2012 CKD Guideline: behind the scenes, need for guidance, and a framework for moving forward

A Levin, PE Stevens - Kidney international, 2014 - Elsevier
The 2012 KDIGO Guideline for CKD evaluation, classification, and management has
updated the original 2002 KDOQI Guidelines, using newer data and addressing issues …

[HTML][HTML] The contribution of chronic kidney disease to the global burden of major noncommunicable diseases

WG Couser, G Remuzzi, S Mendis, M Tonelli - Kidney international, 2011 - Elsevier
Noncommunicable diseases (NCDs) are the most common causes of premature death and
morbidity and have a major impact on health-care costs, productivity, and growth …

[HTML][HTML] Systematic review: kidney transplantation compared with dialysis in clinically relevant outcomes

M Tonelli, N Wiebe, G Knoll, A Bello, S Browne… - American journal of …, 2011 - Elsevier
Individual studies indicate that kidney transplantation is associated with lower mortality and
improved quality of life compared with chronic dialysis treatment. We did a systematic review …

Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta …

Chronic Kidney Disease Prognosis Consortium - The Lancet, 2010 - Elsevier
BACKGROUND: Substantial controversy surrounds the use of estimated glomerular filtration
rate (eGFR) and albuminuria to define chronic kidney disease and assign its stages. We …

Burden of chronic kidney disease and its risk-attributable burden in 137 low-and middle-income countries, 1990–2019: results from the global burden of disease study …

C Ke, J Liang, M Liu, S Liu, C Wang - BMC nephrology, 2022 - Springer
Background Chronic kidney disease (CKD) is a global public health concern, but its disease
burden and risk-attributable burden in CKD has been poorly studied in low-and middle …