2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling
Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD),
Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS), affect millions of people …
Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS), affect millions of people …
A starring role for stellate cells in the pancreatic cancer microenvironment
MV Apte, JS Wilson, A Lugea, SJ Pandol - Gastroenterology, 2013 - Elsevier
Pancreatic ductal adenocarcinoma is a devastating disease, and patient outcomes have not
improved in decades. Treatments that target tumor cells have largely failed. This could be …
improved in decades. Treatments that target tumor cells have largely failed. This could be …
3D bioprinted neural tissue constructs for spinal cord injury repair
X Liu, M Hao, Z Chen, T Zhang, J Huang, J Dai… - Biomaterials, 2021 - Elsevier
Abstract Three-dimensional (3D) bioprinting has emerged as a promising approach to
fabricate living neural constructs with anatomically accurate complex geometries and spatial …
fabricate living neural constructs with anatomically accurate complex geometries and spatial …
Emerging roles of hyaluronic acid bioscaffolds in tissue engineering and regenerative medicine
M Hemshekhar, RM Thushara… - International Journal of …, 2016 - Elsevier
Hyaluronic acid (HA), is a glycosaminoglycan comprised of repeating disaccharide units of
N-acetyl-d-glucosamine and d-glucuronic acid. HA is synthesized by hyaluronan synthases …
N-acetyl-d-glucosamine and d-glucuronic acid. HA is synthesized by hyaluronan synthases …
Arrested preoligodendrocyte maturation contributes to myelination failure in premature infants
Objective: The major form of magnetic resonance imaging–defined white matter injury (WMI)
comprises diffuse lesions where the burden of small necrotic foci (microscopic necrosis) is …
comprises diffuse lesions where the burden of small necrotic foci (microscopic necrosis) is …
Semi-interpenetrating polymer network of hyaluronan and chitosan self-healing hydrogels for central nervous system repair
Y Liu, YH Hsu, APH Huang, S Hsu - ACS Applied Materials & …, 2020 - ACS Publications
The repair of the central nervous system (CNS) is a major challenge because of the difficulty
for neurons or axons to regenerate after damages. Injectable hydrogels have been …
for neurons or axons to regenerate after damages. Injectable hydrogels have been …
Three-dimensional electroconductive hyaluronic acid hydrogels incorporated with carbon nanotubes and polypyrrole by catechol-mediated dispersion enhance …
Electrically conductive hyaluronic acid (HA) hydrogels incorporated with single-walled
carbon nanotubes (CNTs) and/or polypyrrole (PPy) were developed to promote …
carbon nanotubes (CNTs) and/or polypyrrole (PPy) were developed to promote …
Three-dimensional printing of nanomaterial scaffolds for complex tissue regeneration
CM O'Brien, B Holmes, S Faucett… - Tissue Engineering Part …, 2015 - liebertpub.com
Three-dimensional (3D) printing has recently expanded in popularity, and become the
cutting edge of tissue engineering research. A growing emphasis from clinicians on patient …
cutting edge of tissue engineering research. A growing emphasis from clinicians on patient …
3D in vitro modeling of the central nervous system
AM Hopkins, E DeSimone, K Chwalek… - Progress in …, 2015 - Elsevier
There are currently more than 600 diseases characterized as affecting the central nervous
system (CNS) which inflict neural damage. Unfortunately, few of these conditions have …
system (CNS) which inflict neural damage. Unfortunately, few of these conditions have …
Nerve fibers in the tumor microenvironment in neurotropic cancer—pancreatic cancer and cholangiocarcinoma
X Tan, S Sivakumar, J Bednarsch, G Wiltberger… - Oncogene, 2021 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) and cholangiocarcinoma (CCA) are both deadly
cancers and they share many biological features besides their close anatomical location …
cancers and they share many biological features besides their close anatomical location …