Convection-enhanced delivery: connection to and impact of interstitial fluid flow

CA Stine, JM Munson - Frontiers in oncology, 2019 - frontiersin.org
Convection-enhanced delivery (CED) is a method used to increase transport of therapeutics
in and around brain tumors. CED works through locally applying a pressure differential to …

AAV viral vector delivery to the brain by shape-conforming MR-guided infusions

KS Bankiewicz, V Sudhakar, L Samaranch… - Journal of Controlled …, 2016 - Elsevier
Gene transfer technology offers great promise as a potential therapeutic approach to the
brain but has to be viewed as a very complex technology. Success of ongoing clinical gene …

Safety and tolerability of MRI-guided infusion of AAV2-hAADC into the mid-brain of nonhuman primate

W San Sebastian, AP Kells, J Bringas… - … Therapy-Methods & …, 2014 - cell.com
Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare, autosomal-recessive
neurological disorder caused by mutations in the DDC gene that leads to an inability to …

Can 3D artificial intelligence models outshine 2D ones in the detection of intracranial metastatic tumors on magnetic resonance images?

YC Sun, AT Hsieh, ST Fang, HM Wu… - Journal of the …, 2021 - journals.lww.com
Background: This study aimed to compare the prediction performance of two-dimensional
(2D) and three-dimensional (3D) semantic segmentation models for intracranial metastatic …

Reliability and reproducibility of manual and automated volumetric measurements of periapical lesions

EM Aoki, R Abdala-Júnior, JX de Oliveira, ES Arita… - Journal of …, 2015 - Elsevier
Introduction The present study aimed to test the reliability and reproducibility of 2 methods:
manual and automated segmentation (using a threshold-based region growing algorithm) …

Meningioma Relational Database Curation Using A Pacs-Integrated Tool For Collection Of Clinical And Imaging Features

R Mclean - 2024 - elischolar.library.yale.edu
Meningiomas are the most common primary intracranial neoplasm seen in adults, and
despite the largely benign nature of these tumors, they are associated with significant …

Medical Decision Making Based 5D Cardiac MRI Segmentation Tools

H Sakly, M Said, M Tagina - International Conference on Intelligent …, 2022 - Springer
In this survey, a comparison study between various tools in medical segmentation was
proposed. This study serves to evaluate and estimate the adequacy and the impact of the …

Optimizing therapeutic agent delivery to malignant gliomas via convection-enhanced delivery

EOY Campbell - 2023 - repositories.lib.utexas.edu
Convection-enhanced delivery (CED) is a promising investigational strategy for
locoregionally administering therapeutic agents directly into the brain parenchyma to treat …

Estimating brain volume loss after radiation therapy in children treated for posterior fossa tumors (Corpus callosum and whole brain volume changes following …

E Szychot, KK Seunarine, CA Robles, H Mandeville… - 2020 - repository.icr.ac.uk
BACKGROUND: More than half of pediatric tumors of central nervous system (CNS)
primarily originate in the posterior fossa and are conventionally treated with radiation …

[PDF][PDF] Investigation of in vitro antioxidant and cytotoxic potential of Triphala methanol extract in different ratios

SSK Upoma - 2020 - dspace.bracu.ac.bd
Triphala is comprised of Bibhitaki Amalaki and Haritaki and its methanol extract was chosen
for the In vitro antioxidant and cytotoxic potential studies. Firstly, in the DPPH test the IC50 …