Differential microRNA (miRNA or miR) regulation is linked to the development and progress
of many diseases, including inflammatory bowel disease (IBD). It is well-established that …

Milk-derived extracellular vesicles (mEVs) have been proposed as a potential nanomedicine
for intestinal disorders; however, their impact on intestinal barrier integrity in gut …

MicroRNAs are small non-coding RNAs regulating gene expression at the post-
transcriptional level. The regulation of microRNA expression in the gut intestine is gradually …

Bone marrow mesenchymal stem cells (MSCs) have demonstrated therapeutic effects for
colitis through immunomodulation and anti-inflammation. However, whether MSC-derived …

Objective: To investigate the mechanism of immature dendritic cells-derived exosomes
(imDECs) in the regulation of T cell differentiation and immune tolerance in renal allograft …

As a vital pivot for the human circulatory system, the brain-gut axis is now being considered
as an important channel for many of the small immune molecules' transductions, including …

Pre-clinical models and clinical studies highlight the significant impact of the host–
microbiota relationship on cancer development and treatment, supporting the emerging …

Abstract MicroRNA (miR)-219a-5p has been implicated in the development of numerous
progression of carcinoma and autoimmune diseases. However, whether miR-219a-5p is …

Inflammatory bowel disease (IBD) is a persistent inflammatory illness of the gastrointestinal
tract (GIT) triggered by an inappropriate immune response to environmental stimuli in …

Metabolic imbalance leading to inflammatory hypoxia and stabilization of hypoxia-inducible
transcription factors (HIFs) is a hallmark of inflammatory bowel diseases. We hypothesize …