Drug resistance remains the major cause of cancer treatment failure especially at the late
stage of the disease. However, based on their versatile chemistry, metal and metalloid …

More than 10 million death tolls in 2020 were reported as a result of heinous impact of
cancer, making it second most prime cause of death after cardiovascular diseases. In …

The increasing impact of organometallic complexes of group 8–10 metals academically and
industrially over the years demonstrates remarkable progress in harvesting useful reagents …

Due to these limitations of platinum-based drugs, it has now become a challenge for
researchers to find out a potential scaffold furnished with indispensable properties like …

Colorectal cancer (CRC) is one of the most common malignancies and one of the leading
causes of cancer-related death worldwide, urging the need for new and more efficient …

The search for more effective and selective drugs to overcome cancer multidrug resistance
is urgent. As such, a new series of ruthenium-cyclopentadienyl (“RuCp”) compounds with …

The need for new therapeutic approaches for triple-negative breast cancer is a clinically
relevant problem that needs to be solved. Using a multi-targeting approach to enhance …

Two new ruthenium complexes,[Ru (η 5-Cp)(PPh 3)(2, 2'-bipy-4, 4'-R)]+ with R=-CH 2 OH
(Ru1) or dibiotin ester (Ru2) were synthesized and fully characterized. Both compounds …

Ruthenium compounds are promising anticancer candidates owing to their lower side-
effects and encouraging activities against resistant tumors. Half-sandwich piano-stool type …

Ruthenium-based complexes currently attract great attention as they hold promise to replace
platinum-based drugs as a first line cancer treatment. Whereas ruthenium arene complexes …