[HTML][HTML] Lipid metabolism and cancer
Dysregulation in lipid metabolism is among the most prominent metabolic alterations in
cancer. Cancer cells harness lipid metabolism to obtain energy, components for biological …
cancer. Cancer cells harness lipid metabolism to obtain energy, components for biological …
Ubiquitin–proteasome system (UPS) as a target for anticancer treatment
J Park, J Cho, EJ Song - Archives of pharmacal research, 2020 - Springer
The ubiquitin–proteasome system (UPS) plays an important role in the cellular processes for
protein quality control and homeostasis. Dysregulation of the UPS has been implicated in …
protein quality control and homeostasis. Dysregulation of the UPS has been implicated in …
The role of ubiquitination and deubiquitination in cancer metabolism
T Sun, Z Liu, Q Yang - Molecular cancer, 2020 - Springer
Metabolic reprogramming, including enhanced biosynthesis of macromolecules, altered
energy metabolism, and maintenance of redox homeostasis, is considered a hallmark of …
energy metabolism, and maintenance of redox homeostasis, is considered a hallmark of …
[HTML][HTML] Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention
With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …
Hepatocellular carcinoma-derived exosomal miRNA-21 contributes to tumor progression by converting hepatocyte stellate cells to cancer-associated fibroblasts
Y Zhou, H Ren, B Dai, J Li, L Shang, J Huang… - Journal of Experimental & …, 2018 - Springer
Background Hepatocellular carcinoma (HCC) remains a global challenge due to its high
morbidity and mortality rates as well as poor response to treatment. The communication …
morbidity and mortality rates as well as poor response to treatment. The communication …
Regulation and Metabolic Significance of De Novo Lipogenesis in Adipose Tissues
Z Song, AM Xiaoli, F Yang - Nutrients, 2018 - mdpi.com
De novo lipogenesis (DNL) is a complex and highly regulated process in which
carbohydrates from circulation are converted into fatty acids that are then used for …
carbohydrates from circulation are converted into fatty acids that are then used for …
Fatty acid synthase: an emerging target in cancer
CW Fhu, A Ali - Molecules, 2020 - mdpi.com
In recent years, lipid metabolism has garnered significant attention as it provides the
necessary building blocks required to sustain tumor growth and serves as an alternative fuel …
necessary building blocks required to sustain tumor growth and serves as an alternative fuel …
An overview of cancer treatment modalities
Z Abbas, S Rehman - Neoplasm, 2018 - books.google.com
Cancer is a global issue majorly affecting developing countries. According to a survey, 63%
of deaths due to cancer are reported from developing countries. There are different …
of deaths due to cancer are reported from developing countries. There are different …
Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer
Cell state transitions control the functional behavior of cancer cells. Epithelial-to-
mesenchymal transition (EMT) confers cancer stem cell-like properties, enhanced …
mesenchymal transition (EMT) confers cancer stem cell-like properties, enhanced …
Breaking the chains: structure and function of the deubiquitinases
Ubiquitylation is a reversible protein modification that is implicated in many cellular
functions. Recently, much progress has been made in the characterization of a superfamily …
functions. Recently, much progress has been made in the characterization of a superfamily …