Phase separation is a critical mechanism for partitioning cellular functions by specific
aggregation of biological macromolecules. Recent studies have found that phase separation …

Intrinsically disordered proteins (IDPs) play a vital role in various biological processes and
have attracted increasing attention in the past few decades. Predicting IDPs from the primary …

Many proteins do not fold into a fixed three-dimensional structure, but rather function in a
highly disordered state. These intrinsically disordered proteins pose a unique challenge to …

MicroRNAs (miRNAs) are human post-transcriptional regulators in humans, which are
involved in regulating various physiological processes by regulating the gene expression …

Prediction of essential genes in a life organism is one of the central tasks in synthetic
biology. Computational predictors are desired because experimental data is often …

Intrinsically disordered regions (IDRs) represent at least one-third of the human proteome
and defy the established structure-function paradigm. Because IDRs often have limited …

Intrinsically disordered proteins (IDPs) and regions (IDRs) are a class of functionally
important proteins and regions that lack stable three-dimensional structures under the native …

Human complement is the first line of defence against invading pathogens and is involved in
tissue homeostasis. Complement-targeted therapies to treat several diseases caused by a …

Intrinsically disordered proteins and regions (IDPs/IDRs) are functionally important proteins
and regions that exist as highly dynamic conformations under natural physiological …

Disordered linkers (DLs) are intrinsically disordered regions that facilitate movement
between adjacent functional regions/domains, contributing to many key cellular functions …