[HTML][HTML] Percutaneous endoscopic gastrostomy–Too often? Too late? Who are the right patients for gastrostomy?
CG Dietrich, K Schoppmeyer - World journal of gastroenterology, 2020 - ncbi.nlm.nih.gov
Percutaneous endoscopic gastrostomy is an established method to provide nutrition to
patients with restricted oral uptake of fluids and calories. Here, we review the methods …
patients with restricted oral uptake of fluids and calories. Here, we review the methods …
[HTML][HTML] Metabolomics profile in gastrointestinal cancers: Update and future perspectives
Despite recent progress in diagnosis and therapy, gastrointestinal (GI) cancers remain one
of the most important causes of death with a poor prognosis due to late diagnosis. Serum …
of the most important causes of death with a poor prognosis due to late diagnosis. Serum …
[HTML][HTML] GYS1 induces glycogen accumulation and promotes tumor progression via the NF-κB pathway in Clear Cell Renal Carcinoma
S Chen, Q Huang, Y Huang, X Yang, M Yang, Y He… - Theranostics, 2020 - ncbi.nlm.nih.gov
Metabolism reprogramming is a hallmark of many cancer types. We focused on clear cell
renal carcinoma (ccRCC) which is characterized by its clear and glycogen-enriched …
renal carcinoma (ccRCC) which is characterized by its clear and glycogen-enriched …
Emerging glyco-risk prediction model to forecast response to immune checkpoint inhibitors in colorectal cancer
P Qiu, X Chen, C Xiao, M Zhang, H Wang… - Journal of cancer …, 2023 - Springer
Background Aberrant glycosylation is one of the most common post-translational
modifications leading to heterogeneity in colorectal cancer (CRC). This study aims to …
modifications leading to heterogeneity in colorectal cancer (CRC). This study aims to …
Metabolic flux analysis of 3D spheroids reveals significant differences in glucose metabolism from matched 2D cultures of colorectal cancer and pancreatic ductal …
Background Most in vitro cancer cell experiments have been performed using 2D models.
However, 3D spheroid cultures are increasingly favored for being more representative of in …
However, 3D spheroid cultures are increasingly favored for being more representative of in …
Glucose transporter-1 cooperating with AKT signaling promote gastric cancer progression
D Zhou, L Jiang, L Jin, Y Yao, P Wang… - Cancer Management …, 2020 - Taylor & Francis
Objective High expression of GLUT1 has been observed in numerous solid cancers,
facilitating glucose consumption for supporting tumor cell survival. The altered metabolic …
facilitating glucose consumption for supporting tumor cell survival. The altered metabolic …
High PYGL expression predicts poor prognosis in human gliomas
C Zhao, C Hua, C Li, R Zheng, X Li - Frontiers in Neurology, 2021 - frontiersin.org
Background: PYGL has been reported as a glycogen degradation-related gene, which is up-
regulated in many tumors. This study was designed to investigate the predictive value of …
regulated in many tumors. This study was designed to investigate the predictive value of …
Three-dimensional, scaffolded tumor model to study cell-driven microenvironment effects and therapeutic responses
KJ Ornell, KS Mistretta, E Newman… - ACS Biomaterials …, 2019 - ACS Publications
Development of novel therapeutics is limited by a lack of accurate preclinical models for
testing, specifically the inability of traditional 2D culture (monolayer) to accurately mimic in …
testing, specifically the inability of traditional 2D culture (monolayer) to accurately mimic in …
Abnormality of apico–basal polarity in adenocarcinoma
K Onuma, M Inoue - Cancer Science, 2022 - Wiley Online Library
Apico–basal polarity is a fundamental property of the epithelium that functions as a barrier,
holds cells together, and determines the directions of absorption and secretion. Apico–basal …
holds cells together, and determines the directions of absorption and secretion. Apico–basal …
Adverse histologic features in colorectal nonpedunculated malignant polyps with nodal metastasis
Tumor differentiation, lymphovascular invasion, margin status, polyp shape, and size are
important parameters of malignant polyps (pT1) indicating possible node metastasis, which …
important parameters of malignant polyps (pT1) indicating possible node metastasis, which …