Percutaneous endoscopic gastrostomy is an established method to provide nutrition to
patients with restricted oral uptake of fluids and calories. Here, we review the methods …

Despite recent progress in diagnosis and therapy, gastrointestinal (GI) cancers remain one
of the most important causes of death with a poor prognosis due to late diagnosis. Serum …

Metabolism reprogramming is a hallmark of many cancer types. We focused on clear cell
renal carcinoma (ccRCC) which is characterized by its clear and glycogen-enriched …

Background Aberrant glycosylation is one of the most common post-translational
modifications leading to heterogeneity in colorectal cancer (CRC). This study aims to …

Background Most in vitro cancer cell experiments have been performed using 2D models.
However, 3D spheroid cultures are increasingly favored for being more representative of in …

Objective High expression of GLUT1 has been observed in numerous solid cancers,
facilitating glucose consumption for supporting tumor cell survival. The altered metabolic …

Background: PYGL has been reported as a glycogen degradation-related gene, which is up-
regulated in many tumors. This study was designed to investigate the predictive value of …

Development of novel therapeutics is limited by a lack of accurate preclinical models for
testing, specifically the inability of traditional 2D culture (monolayer) to accurately mimic in …

Apico–basal polarity is a fundamental property of the epithelium that functions as a barrier,
holds cells together, and determines the directions of absorption and secretion. Apico–basal …

Tumor differentiation, lymphovascular invasion, margin status, polyp shape, and size are
important parameters of malignant polyps (pT1) indicating possible node metastasis, which …