The unique physiological and genetic characteristics of individuals influence their reactions
to different dietary constituents and nutrients. This notion is the foundation of personalized …

Immune checkpoint inhibitors (ICIs) have emerged as an integral component of the
management of various cancers and have contributed to significant improvements in overall …

Colorectal cancer (CRC), the third most common cancer worldwide, develops mainly due to
the accumulation of genetic and epigenetic changes over many years. Substantial evidence …

The field of microbial ecology, evolution, and biodiversity (EEB) is at the leading edge of
understanding how microbes shape our biosphere and influence the well-being of …

Background Preoperative radiation therapy (preRT) is a fundamental aspect of neoadjuvant
treatment for rectal cancer (RC), but the response to this treatment remains unsatisfactory …

Immunotherapy with immune checkpoint inhibitors represents a revolutionary approach to
the treatment of solid tumors, including malignant melanoma, lung cancer, and …

Background: The human digestive system contains approximately 100 trillion bacteria. The
gut microbiota is an emerging field of research that is associated with specific biological …

Recent advances have significantly deepened our understanding of the pathogenesis of
neuroendocrine neoplasms (NENs), particularly regarding the tumor microenvironment …

The effectiveness of programmed cell death protein 1 (PD-1) and programmed death ligand
1 (PD-L1) immunotherapies in cancer treatment is significantly influenced by the variable …

The world around us is teeming with microorganisms that play crucial roles in shaping our
environment and health. In recent years, scientists have made remarkable strides in …