[HTML][HTML] The biological role and immunotherapy of gangliosides and GD3 synthase in cancers

S Cao, X Hu, S Ren, Y Wang, Y Shao, K Wu… - Frontiers in Cell and …, 2023 - frontiersin.org
Gangliosides are a large subfamily of glycosphingolipids that broadly exist in the nervous
system and interact with signaling molecules in the lipid rafts. GD3 and GD2 are two types of …

[HTML][HTML] Variant rs8400 enhances ALKBH5 expression through disrupting miR-186 binding and promotes neuroblastoma progression

Q Guan, H Lin, W Hua, L Lin, J Liu, L Deng… - Chinese Journal of …, 2023 - ncbi.nlm.nih.gov
Objective AlkB homolog 5 (ALKBH5) has been proven to be closely related to tumors.
However, the role and molecular mechanism of ALKBH5 in neuroblastomas have rarely …

[HTML][HTML] METTL14 gene polymorphisms confer neuroblastoma susceptibility: an eight-center case-control study

Z Zhuo, H Lu, J Zhu, RX Hua, Y Li, Z Yang… - … Therapy-Nucleic Acids, 2020 - cell.com
Neuroblastoma is the primary cause of cancer death in childhood. METTL14 is tightly linked
to cancer. However, whether single-nucleotide polymorphisms (SNPs) in the METTL14 gene …

Association between METTL3 gene polymorphisms and neuroblastoma susceptibility: A nine‐centre case‐control study

J Bian, Z Zhuo, J Zhu, Z Yang, Z Jiao… - Journal of Cellular …, 2020 - Wiley Online Library
Neuroblastoma ranks as the most commonly seen and deadly solid tumour in infancy. The
aberrant activity of m6A‐RNA methyltransferase METTL3 is involved in human cancers …

LIN28A gene polymorphisms modify neuroblastoma susceptibility: A four‐centre case‐control study

RX Hua, Z Zhuo, L Ge, J Zhu, L Yuan… - Journal of Cellular …, 2020 - Wiley Online Library
Neuroblastoma ranks the most common seen solid tumour in childhood. Overexpression of
LIN28A gene has been linked to the development of multiple human malignancies, but the …

Targeted elimination of myeloid-derived suppressor cells via regulation of the STAT pathway alleviates tumor immunosuppression in neuroblastoma

W Xu, S Li, M Li, X Yang, S Xie, L Lin, G Li, H Zhou - Immunology Letters, 2021 - Elsevier
Neuroblastoma (NB) has high morality rates and is the most common malignant tumor found
in children. High aggregation of myeloid-derived suppressor cells (MDSCs) in the tumor …

Transplantation for ultra high-risk neuroblastoma patients: effect of tandem autologous stem cell transplantation

E Yılmaz, MB Samur, A Özcan, E Ünal… - Journal of Health …, 2021 - dergipark.org.tr
Aim: Neuroblastoma is a tumor with a high mortality rate originating from primitive
sympathetic ganglion cells. In recent years, the definition of" ultra high-risk" has been used …

[HTML][HTML] Immunohistochemical expression of anaplastic lymphoma kinase in neuroblastoma and its relations with some clinical and histopathological features

TDA Phan, TQ Nguyen, NT To, TL Thanh… - Journal of Pathology …, 2024 - ncbi.nlm.nih.gov
Background Anaplastic lymphoma kinase (ALK) mutations have been identified as a
prominent cause of some familial and sporadic neuroblastoma (NB). ALK expression in NB …

Combined detection of copy number variations of MYCN and ALK using droplet digital polymerase chain reaction to identify high-risk patients with neuroblastoma

T Trivedi, K Panchal, N Bhalala, P Trivedi, H Panchal - World Neurosurgery, 2022 - Elsevier
Objective The current study sought to explore the significance of copy number variations
(CNVs) of MYCN (v-myc myelocytomatosis viral related oncogene, neuroblastoma derived …

Expression of GD2 and GD3 in peripheral neuroblastic tumors

X Wei, S Li, Y Wang - Indian Journal of Pathology and …, 2024 - journals.lww.com
Purpose: The aim of this study was to explore the correlation between the expression of GD2
and GD3 and the histopathological types, risk groups, and chemotherapy in peripheral …