The role of acidosis in the pathogenesis of severe forms of COVID-19

YD Nechipurenko, DA Semyonov, IA Lavrinenko… - Biology, 2021 - mdpi.com
Simple Summary Recently, several studies have shown that acidosis, which is increased
acidity in the blood and other body tissues, is often associated with severe COVID-19. In this …

A review: Antibody-dependent enhancement in COVID-19: The not so friendly side of antibodies

GA Sánchez-Zuno, MG Matuz-Flores… - International journal …, 2021 - journals.sagepub.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), represents an unprecedented global public health …

An update review of globally reported SARS-CoV-2 vaccines in preclinical and clinical stages

H Motamedi, MM Ari, S Dashtbin, M Fathollahi… - International …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the rapidly spreading pandemic COVID-19 in the world. As an effective therapeutic strategy …

Change of antigenic determinants of SARS-CoV-2 virus S-protein as a possible cause of antibody-dependent enhancement of virus infection and cytokine storm

YD Nechipurenko, AA Anashkina, OV Matveeva - Biophysics, 2020 - Springer
A hypothesis is proposed that the cytokine storm syndrome, which complicates COVID-19 in
some patients, is a consequence of antibody-dependent enhancement of virus infection …

[HTML][HTML] Oral subunit SARS-CoV-2 vaccine induces systemic neutralizing IgG, IgA and cellular immune responses and can boost neutralizing antibody responses …

J Pitcovski, N Gruzdev, A Abzach, C Katz, R Ben-Adiva… - Vaccine, 2022 - Elsevier
The rapid spread of the COVID-19 pandemic, with its devastating medical and economic
impacts, triggered an unprecedented race toward development of effective vaccines. The …

Antibody-dependent enhancement with a focus on SARS-coV-2 and anti-glycan antibodies

MM Ziganshina, NV Shilova, EO Khalturina… - Viruses, 2023 - mdpi.com
Antibody-dependent enhancement (ADE) is a phenomenon where virus-specific antibodies
paradoxically cause enhanced viral replication and/or excessive immune responses …

Efficacy of a live attenuated highly pathogenic PRRSV vaccine against a NADC30-like strain challenge: Implications for ADE of PRRSV

X Chen, X Zhou, T Guo, S Qiao, Z Guo, R Li… - BMC Veterinary …, 2021 - Springer
Background Porcine reproductive and respiratory syndrome virus (PRRSV) infection can
cause severe reproductive failure in sows and respiratory distress in pigs of all ages, leading …

Theoretical explanation for the rarity of antibody-dependent enhancement of infection (ADE) in COVID-19

AE Boldova, JD Korobkin, YD Nechipurenko… - International Journal of …, 2022 - mdpi.com
Global vaccination against the SARS-CoV-2 virus has proved to be highly effective.
However, the possibility of antibody-dependent enhancement of infection (ADE) upon …

Th2 and Th17‐associated immunopathology following SARS‐CoV‐2 breakthrough infection in Spike‐vaccinated ACE2‐humanized mice

T Zhang, N Magazine, MC McGee… - Journal of Medical …, 2024 - Wiley Online Library
Vaccines have demonstrated remarkable effectiveness in protecting against COVID‐19;
however, concerns regarding vaccine‐associated enhanced respiratory diseases (VAERD) …

An outline of contributing vaccine technologies for SARS CoV2 advancing in clinical and preclinical phase-trials

SS Naz, I Munir - Recent patents on biotechnology, 2022 - ingentaconnect.com
Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV2) is an RNA
virus involving 4 structural and 16 non-structural proteins, and exhibiting high transmission …