[HTML][HTML] Biomedical applications of microfluidic devices: a review
Both passive and active microfluidic chips are used in many biomedical and chemical
applications to support fluid mixing, particle manipulations, and signal detection. Passive …
applications to support fluid mixing, particle manipulations, and signal detection. Passive …
Controlling the biodistribution and clearance of nanomedicines
Nanomedicines improve drug bioavailability, the dose–response relationship, targeting
ability, efficacy and safety compared to conventional freely administered drugs …
ability, efficacy and safety compared to conventional freely administered drugs …
[HTML][HTML] Human disease models in drug development
A Loewa, JJ Feng, S Hedtrich - Nature reviews bioengineering, 2023 - nature.com
Biomedical research is undergoing a paradigm shift towards approaches centred on human
disease models owing to the notoriously high failure rates of the current drug development …
disease models owing to the notoriously high failure rates of the current drug development …
[HTML][HTML] Microfluidic organ-on-a-chip: a guide to biomaterial choice and fabrication
UMN Cao, Y Zhang, J Chen, D Sayson, S Pillai… - International journal of …, 2023 - mdpi.com
Organ-on-A-chip (OoAC) devices are miniaturized, functional, in vitro constructs that aim to
recapitulate the in vivo physiology of an organ using different cell types and extracellular …
recapitulate the in vivo physiology of an organ using different cell types and extracellular …
Intelligent biomaterialomics: molecular design, manufacturing, and biomedical applications
Y Yi, HW An, H Wang - Advanced Materials, 2023 - Wiley Online Library
Materialomics integrates experiment, theory, and computation in a high‐throughput manner,
and has changed the paradigm for the research and development of new functional …
and has changed the paradigm for the research and development of new functional …
Biosensors integrated 3D organoid/organ-on-a-chip system: A real-time biomechanical, biophysical, and biochemical monitoring and characterization
As a full-fidelity simulation of human cells, tissues, organs, and even systems at the
microscopic scale, Organ-on-a-Chip (OOC) has significant ethical advantages and …
microscopic scale, Organ-on-a-Chip (OOC) has significant ethical advantages and …
Nature-inspired micropatterns
Micropatterned materials have developed in nature over 3.8 billion years, with remarkable
performance. Nature inspiration is the process of understanding biological mechanisms and …
performance. Nature inspiration is the process of understanding biological mechanisms and …
Illuminating the oral microbiome and its host interactions: animal models of disease
G Hajishengallis - FEMS Microbiology Reviews, 2023 - academic.oup.com
Periodontitis and caries are driven by complex interactions between the oral microbiome
and host factors, ie inflammation and dietary sugars, respectively. Animal models have been …
and host factors, ie inflammation and dietary sugars, respectively. Animal models have been …
Vat photopolymerization 3D printed microfluidic devices for organ-on-a-chip applications
Organs-on-a-chip, or OoCs, are microfluidic tissue culture devices with micro-scaled
architectures that repeatedly achieve biomimicry of biological phenomena. They are well …
architectures that repeatedly achieve biomimicry of biological phenomena. They are well …
Advances in TEER measurements of biological barriers in microphysiological systems
Biological barriers are multicellular structures that precisely regulate the transport of ions,
biomolecules, drugs, cells, and other organisms. Transendothelial/epithelial electrical …
biomolecules, drugs, cells, and other organisms. Transendothelial/epithelial electrical …