Abstract Background The Wnt signaling pathway is a complex network of protein interactions
that functions most commonly in embryonic development and cancer, but is also involved in …

Cancer is one of the most studied areas of human biology over the past century. Despite
having attracted much attention, hype, and investments, the search to find a cure for cancer …

DEAD-box helicases (DDXs) regulate RNA processing and metabolism by unwinding short
double-stranded (ds) RNAs. Sharing a helicase core composed of two RecA-like domains …

An innovative approach to eliminate HIV-1-infected cells emerging out of latency, the major
hurdle to HIV-1 cure, is to pharmacologically reactivate viral expression and concomitantly …

Colorectal cancer (CRC) is one of the most common gastrointestinal cancers worldwide. It is
a complicated and often fatal cancer, and is related to a high disease-related mortality …

This short review is focused on enzymatic properties of human ATP-dependent RNA
helicase DDX3 and the development of antiviral and anticancer drugs targeting cellular …

Functional specialization of cells and tissues in metazoans require specific gene expression
patterns. Biological processes, thus, need precise temporal and spatial coordination of gene …

Background The aim of this in vitro study was to measure the enhanced anticancer effects of
Res (resveratrol) on PA (paclitaxel) in HepG2 human liver cancer cells. Methods The MTT …

DEAD-box RNA helicases comprise a family within helicase superfamily 2 and make up the
largest group of RNA helicases. They are a profoundly conserved family of RNA-binding …

Long non-coding RNAs (lncRNAs) have been tested to act as important regulator in liver
cancer genesis and progression. LncRNA Nicotinamide Nucleotide Transhydrogenase …