Despite the multiple ongoing and novel initiatives for developing brain-targeted drug
delivery systems, insurmountable obstacles remain. A perfect drug delivery device that can …

The design of a drug that successfully overcomes the constraints imposed by the blood–
brain barrier (BBB, which acts as a gatekeeper to the entry of substances into the brain) …

Microneedle-devices provide a promising alternative to syringe-injection-based
administration of chemotherapeutics. Dissolvable polymeric microneedles provide …

Traditional anti-cancer treatments are inefficient against glioblastoma, which remains one of
the deadliest and most aggressive cancers. Nano-drugs could help to improve this situation …

Nanoformulation based drug delivery is one of the most important research areas in the field
of nanomedicine, which provides promising alternatives to the limitations of conventional …

The incidence of brain metastases has increased in the last 10 years. However, the survival
of patients with brain metastases remains poor and challenging in daily practice in medical …

Therapeutic outcome for the treatment of glioma was often limited due to drug resistance
and low permeability of drug across the multiple physiological barriers, including the blood …

A biocompatible nanodrug delivery formulation based on poly (D, L-lactide-co-glycolic) acid
(PLGA), polyethylene glycol (PEG) and superparamagnetic iron oxide nanoparticles has …

Hepatocellular carcinoma (HCC) is one of the major causes of cancer related death globally.
Apigenin, a dietary flavonoid, possesses anti-tumor activity against HCC cells in-vitro …

Brain tumors, especially the most prevalent and aggressive glioblastoma, remain among the
deadliest of all types of cancer due to inefficient theranostic options. They have a limited …