Genomics and pathotypes of the many faces of Escherichia coli

J Geurtsen, M de Been, E Weerdenburg… - FEMS microbiology …, 2022 - academic.oup.com
Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …

Uropathogenic Escherichia coli (UPEC)-Associated Urinary Tract Infections: The Molecular Basis for Challenges to Effective Treatment

S Whelan, B Lucey, K Finn - Microorganisms, 2023 - mdpi.com
Urinary tract infections (UTIs) are among the most common bacterial infections, especially
among women and older adults, leading to a significant global healthcare cost burden …

Characterization of Uropathogenic Escherichia coli Reveals Hybrid Isolates of Uropathogenic and Diarrheagenic (UPEC/DEC) E. coli

RHS Tanabe, RCB Dias, H Orsi, DRP de Lira… - Microorganisms, 2022 - mdpi.com
(1) Background: Pathogenic Escherichia coli are divided into two groups: diarrheagenic
(DEC) and extraintestinal pathogenic (ExPEC) E. coli. ExPEC causing urinary tract infections …

Host-pathogen interaction: Enterobacter cloacae exerts different adhesion and invasion capacities against different host cell types

E Frutos-Grilo, V Kreling, A Hensel, S Campoy - Plos one, 2023 - journals.plos.org
New antibiotics are urgently needed due to the huge increase of multidrug-resistant
bacteria. The underexplored gram-negative bacterium Enterobacter cloacae is known to …

Fluorothiazinon inhibits the virulence factors of uropathogenic Escherichia coli involved in the development of urinary tract infection

EA Koroleva, AV Soloveva, EY Morgunova… - The Journal of …, 2023 - nature.com
Uropathogenic Escherichia coli (UPEC) is the most common pathogenic bacterium
associated with urinary tract infection. Due to the development of antibiotic resistance and …

Ceragenin CSA-13 displays high antibacterial efficiency in a mouse model of urinary tract infection

U Wnorowska, E Piktel, P Deptuła, T Wollny, G Król… - Scientific Reports, 2022 - nature.com
Ceragenins (CSAs) are synthetic, lipid-based molecules that display activities of natural
antimicrobial peptides. Previous studies demonstrated their high in vitro activity against …

Frequency and Diversity of Hybrid Escherichia coli Strains Isolated from Urinary Tract Infections

JAS Nascimento, FF Santos, TB Valiatti… - Microorganisms, 2021 - mdpi.com
(1) Background: Hybrid uropathogenic Escherichia coli (UPEC) strains carry virulence
markers of the diarrheagenic E. coli (DEC) pathotypes, which may increase their virulence …

Role of aggregate-forming pilus (AFP) in adherence and colonization of both intestinal and urinary tracts

PA Schüroff, CM Abe, JW Silva, C de Paula Coelho… - Virulence, 2022 - Taylor & Francis
Hybrid-pathogenic Escherichia coli represent an important group of strains associated with
intestinal and extraintestinal infections. Recently, we described strain UPEC-46, a …

Molecular Study on Virulence and Resistance Genes of ST131 Clone (Uropathogenic/Enteropathogenic Escherichia Coli) Hybrids in Children

R Shahbazi, M Alebouyeh, S Shahkolahi… - Future …, 2023 - Taylor & Francis
Aim: To analyze ST131 clones and other characteristics in uropathogenic and atypical
enteropathogenic Escherichia coli hybrids. Methods: Samples were collected from children …

Detection and characterization of hybrid uropathogenic Escherichia coli strains among E. coli isolates causing community-acquired urinary tract infection

M Yousefipour, SE Rezatofighi… - Journal of Medical …, 2023 - microbiologyresearch.org
Introduction. The main aetiological agent of urinary tract infection (UTI) is Escherichia coli,
categorized as uropathogenic E. coli (UPEC). The genome of UPEC shows a high degree of …