Cytochrome P450 enzymes in fungal natural product biosynthesis

X Zhang, J Guo, F Cheng, S Li - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 2015 to the end of 2020 Fungal-derived polyketides, non-ribosomal peptides,
terpenoids and their hybrids contribute significantly to the chemical space of total natural …

Oxidative cyclization in natural product biosynthesis

MC Tang, Y Zou, K Watanabe, CT Walsh… - Chemical …, 2017 - ACS Publications
Oxidative cyclizations are important transformations that occur widely during natural product
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …

[HTML][HTML] Refined families of Dothideomycetes: orders and families incertae sedis in Dothideomycetes

S Hongsanan, KD Hyde, R Phookamsak… - Fungal diversity, 2020 - Springer
Numerous new taxa and classifications of Dothideomycetes have been published following
the last monograph of families of Dothideomycetes in 2013. A recent publication by …

Unusual dioxygen-dependent reactions catalyzed by nonheme iron enzymes in natural product biosynthesis

R Ushimaru, I Abe - ACS Catalysis, 2022 - ACS Publications
Nonheme iron-dependent enzymatic reactions play crucial roles in building and modifying
bioactive organic molecules in all major classes of natural product pathways. While the …

Regio-and stereoselective intermolecular phenol coupling enzymes in secondary metabolite biosynthesis

W Hüttel, M Müller - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 2005 to 2020 Phenol coupling is a key reaction in the biosynthesis of important
biopolymers such as lignin and melanin and of a plethora of biarylic secondary metabolites …

Enzymatic dimerization in the biosynthetic pathway of microbial natural products

J Liu, A Liu, Y Hu - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to August 2020 The dramatic increase in the identification of dimeric natural
products generated by microorganisms and plants has played a significant role in drug …

Structural diversity and biological activities of novel secondary metabolites from endophytes

H Gao, G Li, HX Lou - Molecules, 2018 - mdpi.com
Exploration of structurally novel natural products greatly facilitates the discovery of
biologically active pharmacophores that are biologically validated starting points for the …

[HTML][HTML] The photoactivity of natural products–an overlooked potential of phytomedicines?

B Siewert, H Stuppner - Phytomedicine, 2019 - Elsevier
Background Photoactivity, though known for centuries, is only recently shifting back into
focus as a treatment option against cancer and microbial infections. The external factor light …

Endophytic fungi as a source of antibacterial compounds—a focus on gram-negative bacteria

DPD Silva, MS Cardoso, AJ Macedo - Antibiotics, 2022 - mdpi.com
Bacterial resistance has become one of the main motives in the worldwide race for
undescribed antibacterial agents. The difficulties in the treatment of bacterial infections are a …

New phenalenone derivatives from the Hawaiian volcanic soil-associated fungus Penicillium herquei FT729 and their inhibitory effects on indoleamine 2,3 …

JS Yu, SY Jeong, C Li, T Oh, M Kwon, JS Ahn… - Archives of Pharmacal …, 2022 - Springer
Phenalenone derivatives sourced from fungi are polyketides that have attracted significant
interest because of their diverse chemical structures and potential bioactivities. As part of our …