Ischemic stroke is an acute cerebrovascular disease characterized by sudden interruption of
blood flow in a certain part of the brain, leading to serious disability and death. At present …

Endoplasmic reticulum (ER) is the main organelle for protein synthesis, trafficking and
maintaining intracellular Ca2+ homeostasis. The stress response of ER results from the …

Neuronal death and inflammatory response are two common pathological hallmarks of
acute central nervous system injury and chronic degenerative disorders, both of which are …

Stroke is a disastrous neurological disease with high morbidity and mortality. The
mechanism of the pathological process is extremely complicated and unclear. Although …

Intracerebral haemorrhage (ICH) is a devastating subtype of stroke with high morbidity and
mortality. It has been reported that paeonol (PAN) inhibits the progression of ICH. However …

Intracerebral hemorrhage (ICH) is a highly harmful neurological disorder with high rates of
mortality, disability, and recurrence. However, effective therapies are not currently available …

Iron is one of the most crucial elements in the human body. In recent years, a kind of
programmed, non-apoptotic cell death closely related to iron metabolism-called ferroptosis …

Piezo1 is a mechanically-gated calcium channel. Recent studies have shown that Piezo1, a
mechanically-gated calcium channel, can attenuate both psychosine-and …

Intracerebral hemorrhage (ICH) is one of the leading causes of death and long-term
disability worldwide. The ICH is characterized by motor and sensory dysfunction that is …

During intracerebral hemorrhage (ICH), hematoma formation at the site of blood vessel
damage results in local mechanical injury. Subsequently, erythrocytes lyse to release …