Indole alkaloid synthesis facilitated by photoredox catalytic radical cascade reactions
XY Liu, Y Qin - Accounts of chemical research, 2019 - ACS Publications
Conspectus The monoterpene indole alkaloids, containing over 3000 known members and
more than 40 structural types, represent one of the largest natural product families that have …
more than 40 structural types, represent one of the largest natural product families that have …
Chemical diversity and bioactivities of monoterpene indole alkaloids (MIAs) from six Apocynaceae genera
AE Mohammed, ZH Abdul-Hameed, MO Alotaibi… - Molecules, 2021 - mdpi.com
By the end of the twentieth century, the interest in natural compounds as probable sources of
drugs has declined and was replaced by other strategies such as molecular target-based …
drugs has declined and was replaced by other strategies such as molecular target-based …
Analysis of alkaloids (indole alkaloids, isoquinoline alkaloids, tropane alkaloids)
Alkaloids are a large cluster of molecules found in Mother Nature all over the world. They
are all secondary compounds and collection of miscellaneous elements and biomolecules …
are all secondary compounds and collection of miscellaneous elements and biomolecules …
Fischer indole synthesis applied to the total synthesis of natural products
One of the oldest and most useful reactions in organic chemistry is the Fischer indole
synthesis (FIS). It is known to have a wide variety of applications including the synthesis of …
synthesis (FIS). It is known to have a wide variety of applications including the synthesis of …
Ruthenium(II)‐Catalyzed C−H Activation of Imidamides and Divergent Couplings with Diazo Compounds: Substrate‐Controlled Synthesis of Indoles and 3H‐Indoles
Y Li, Z Qi, H Wang, X Yang, X Li - … Chemie International Edition, 2016 - Wiley Online Library
Indoles are an important structural motif that is commonly found in biologically active
molecules. In this work, conditions for divergent couplings between imidamides and …
molecules. In this work, conditions for divergent couplings between imidamides and …
Enantioselective palladium-catalyzed allylic alkylation reactions in the synthesis of Aspidosperma and structurally related monoterpene indole alkaloids
BP Pritchett, BM Stoltz - Natural product reports, 2018 - pubs.rsc.org
Covering: up to the end of 2017 Enantioselective Pd-catalyzed allylic alkylations of prochiral
enolates represent a powerful tool for the construction of all-carbon quaternary …
enolates represent a powerful tool for the construction of all-carbon quaternary …
A Gold‐Catalyzed Domino Cyclization Enabling Rapid Construction of Diverse Polyheterocyclic Frameworks
Y He, Z Li, K Robeyns, L Van Meervelt… - Angewandte Chemie …, 2018 - Wiley Online Library
We report herein an efficient gold (I)‐catalyzed post‐Ugi domino dearomatization/ipso‐
cyclization/Michael sequence that enables access to libraries of diverse (hetero) arene …
cyclization/Michael sequence that enables access to libraries of diverse (hetero) arene …
Harnessing the chemistry of the indole heterocycle to drive discoveries in biology and medicine
VM Norwood IV, RW Huigens III - ChemBioChem, 2019 - Wiley Online Library
Indole‐containing compounds demonstrate an array of biological activities relevant to
numerous human diseases. The biological activities of diverse indole‐based agents are …
numerous human diseases. The biological activities of diverse indole‐based agents are …
[HTML][HTML] Applications of ultrasound in total synthesis of bioactive natural products: A promising green tool
S Majhi - Ultrasonics Sonochemistry, 2021 - Elsevier
Total synthesis is frequently compared to climbing as it provides a suitable route to reach a
high point from the floor, the complex natural product from simple and commercially …
high point from the floor, the complex natural product from simple and commercially …
Asymmetric Total Syntheses of Kopsia Indole Alkaloids
L Leng, X Zhou, Q Liao, F Wang, H Song… - Angewandte …, 2017 - Wiley Online Library
The asymmetric total syntheses of a group of structurally complex Kopsia alkaloids,(−)‐
kopsine,(−)‐isokopsine,(+)‐methyl chanofruticosinate,(−)‐fruticosine, and (−)‐kopsanone …
kopsine,(−)‐isokopsine,(+)‐methyl chanofruticosinate,(−)‐fruticosine, and (−)‐kopsanone …