Sepsis is a common complication of combat injuries and trauma, and is defined as a life-
threatening organ dysfunction caused by a dysregulated host response to infection. It is also …

Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

Sepsis is expected to have a substantial impact on public health and cost as its prevalence
increases. Factors contributing to increased prevalence include a progressively aging …

COVID-19 is a clinical syndrome ranging from mild symptoms to severe pneumonia that
often leads to respiratory failure, need for mechanical ventilation, and death. Most of the lung …

Emerged evidence has indicated that immunosuppression is involved in the occurrence and
development of sepsis. To provide clinical practice recommendations on the immune …

Sepsis remains a common, serious, and heterogeneous clinical entity that is difficult to
define adequately. Despite its importance as a public health problem, efforts to develop and …

Background: Sepsis is a deadly immunological disorder and its pathophysiology is still
poorly understood. We aimed to determine if specific pro-inflammatory and anti-inflammatory …

Sepsis remains a critical problem with significant morbidity and mortality even in the modern
era of critical care management. Multiple derangements exist in sepsis involving several …

Highlights•Immunomonitoring identifies septic patients who could benefit from
immunotherapy.•Immune stratification should be considered in clinical trials design in …

There is no Food and Drug Administration-approved treatment for acute respiratory distress
syndrome (ARDS), in spite of the relatively large number of patients with the diagnosis. In …