Role of STAT3 in the initiation, progression, proliferation and metastasis of breast cancer and strategies to deliver JAK and STAT3 inhibitors
YH Dinakar, H Kumar, SL Mudavath, R Jain, R Ajmeer… - Life Sciences, 2022 - Elsevier
Introduction Breast cancer (BC) accounts for the majority of cancers among the female
population. Anomalous activation of various signaling pathways has become an issue of …
population. Anomalous activation of various signaling pathways has become an issue of …
In vitro-in vivo correlation in nanocarriers: From protein corona to therapeutic implications
Understanding and establishing a link between the physicochemical characteristics of
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …
nanoparticles (NPs) and their biological interactions poses to be a great challenge in the …
Pharmacological effects of shikonin and its potential in skin repair: A review
Y Song, Q Ding, Y Hao, B Cui, C Ding, F Gao - Molecules, 2023 - mdpi.com
Currently, skin injuries have a serious impact on people's lives and socio-economic stress.
Shikonin, a naphthoquinone compound derived from the root of the traditional Chinese …
Shikonin, a naphthoquinone compound derived from the root of the traditional Chinese …
A review of nanostructured delivery systems for the encapsulation, protection, and delivery of silymarin: An emerging nutraceutical
Silymarin exhibits biological activities that may promote human health and wellbeing,
including antioxidant, antimicrobial, anti-inflammatory, and anti-cancer activities …
including antioxidant, antimicrobial, anti-inflammatory, and anti-cancer activities …
Rationally designed nanoparticulate delivery approach for silymarin with natural bio-enhancer: in vitro characterization and in vivo evaluations of hepatoprotective …
The proposed research study accentuates the delivery of drug and natural bioenhancer by
utilizing a nano-platform based on eudragit RL (ERL) for enhanced efficacy, bioavailability …
utilizing a nano-platform based on eudragit RL (ERL) for enhanced efficacy, bioavailability …
Micelle silymarin supplementation to sows' diet from day 109 of gestation to entire lactation period enhances reproductive performance and affects serum hormones …
Q Zhang, JM Ahn, IH Kim - Journal of Animal Science, 2021 - academic.oup.com
The aim of the present study was to explore the influences of varying doses of micelle
silymarin (0%, 0.05%, 0.1%, and 0.2%) supplementation on sows' feed intake, milk yields …
silymarin (0%, 0.05%, 0.1%, and 0.2%) supplementation on sows' feed intake, milk yields …
Pharmaceutical prospects of Silymarin for the treatment of neurological patients: an updated insight
Background Silymarin is a polyphenolic flavonoid complex extricated from dried fruits and
seeds of the plant Silybum marianum L. Chemically, it is a mixture of flavonolignan …
seeds of the plant Silybum marianum L. Chemically, it is a mixture of flavonolignan …
Fisetin-loaded nanostructured lipid carriers: Formulation and evaluations against advanced and metastatic melanoma
H Kumar, P Chand, S Pachal, S Mallick… - Molecular …, 2023 - ACS Publications
Fisetin (Fis), a natural flavonoid with anticancer effects, suffers from delivery constraints.
Fisetin-nanostructured lipid carriers (NLCs) were developed for better efficacy against …
Fisetin-nanostructured lipid carriers (NLCs) were developed for better efficacy against …
Graphene-silymarin-loaded chitosan/gelatin/hyaluronic acid hybrid constructs for advanced full-thickness burn wound management
S Katiyar, AD Tripathi, RK Singh, AK Chaurasia… - International Journal of …, 2024 - Elsevier
Burn wounds (BWs) with extensive blood loss, along with bacterial infections and poor
healing, may become detrimental and pose significant rehabilitation obstacles in medical …
healing, may become detrimental and pose significant rehabilitation obstacles in medical …
Preparation, characterization and evaluation of flavonolignan silymarin effervescent floating matrix tablets for enhanced oral bioavailability
S Ahmad, JA Khan, TN Kausar, MH Mahnashi, A Alasiri… - Molecules, 2023 - mdpi.com
The convenient and highly compliant route for the delivery of active pharmaceutical
ingredients is the tablet. A versatile platform of tablets is available for the delivery of …
ingredients is the tablet. A versatile platform of tablets is available for the delivery of …