Nutrition and breast cancer: a literature review on prevention, treatment and recurrence

P De Cicco, MV Catani, V Gasperi, M Sibilano… - Nutrients, 2019 - mdpi.com
Breast cancer (BC) is the second most common cancer worldwide and the most commonly
occurring malignancy in women. There is growing evidence that lifestyle factors, including …

Efficacy of vitamin D3 supplementation on cancer mortality: Systematic review and individual patient data meta-analysis of randomised controlled trials

S Kuznia, A Zhu, T Akutsu, JE Buring… - Ageing research …, 2023 - Elsevier
To evaluate the effect of vitamin D 3 supplementation on cancer mortality in the general
population and on prognosis in cancer patients, a systematic review and meta-analysis of …

Vitamin D signaling in inflammation and cancer: Molecular mechanisms and therapeutic implications

A El-Sharkawy, A Malki - Molecules, 2020 - mdpi.com
Vitamin D and its active metabolites are important nutrients for human skeletal health. UV
irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the …

The role of vitamin D in breast cancer risk and progression

J Vanhevel, L Verlinden, S Doms… - Endocrine-related …, 2022 - erc.bioscientifica.com
The active form of vitamin D 3, 1, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3), is primarily
known as a key regulator of calcium and phosphate homeostasis. It exerts its biological …

Principal results of the VITamin D and OmegA-3 TriaL (VITAL) and updated meta-analyses of relevant vitamin D trials

JAE Manson, SS Bassuk, JE Buring… - The Journal of steroid …, 2020 - Elsevier
Whether supplemental vitamin D reduces risk of cancer or cardiovascular disease (CVD) is
relatively unexplored in randomized trial settings. The VITamin D and OmegA-3 TriaL …

The effect of vitamin D supplementation on survival in patients with colorectal cancer: systematic review and meta-analysis of randomised controlled trials

PG Vaughan-Shaw, LF Buijs, JP Blackmur… - British journal of …, 2020 - nature.com
Background Low circulating vitamin D levels are associated with poor colorectal cancer
(CRC) survival. We assess whether vitamin D supplementation improves CRC survival …

Mechanisms of action of vitamin D in colon cancer

G Ferrer-Mayorga, MJ Larriba, P Crespo… - The Journal of steroid …, 2019 - Elsevier
Colorectal cancer (CRC) is the neoplasia that is most frequently associated with vitamin D
deficiency in epidemiological and observational studies in terms of incidence and mortality …

Effect of vitamin D supplementation on relapse-free survival among patients with digestive tract cancers: the AMATERASU randomized clinical trial

M Urashima, H Ohdaira, T Akutsu, S Okada, M Yoshida… - Jama, 2019 - jamanetwork.com
Importance Randomized clinical trials of vitamin D supplementation for secondary
prevention in patients with cancer are needed, given positive results of observational …

[HTML][HTML] Repurposing vitamin D for treatment of human malignancies via targeting tumor microenvironment

X Wu, W Hu, L Lu, Y Zhao, Y Zhou, Z Xiao… - … Pharmaceutica Sinica B, 2019 - Elsevier
Tumor cells along with a small proportion of cancer stem cells exist in a stromal
microenvironment consisting of vasculature, cancer-associated fibroblasts, immune cells …

Vitamin D-induced molecular mechanisms to potentiate cancer therapy and to reverse drug-resistance in cancer cells

M Negri, A Gentile, C de Angelis, T Montò, R Patalano… - Nutrients, 2020 - mdpi.com
Increasing interest in studying the role of vitamin D in cancer has been provided by the
scientific literature during the last years, although mixed results have been reported. Vitamin …