The skin is the largest organ of the human body, and its dysfunction is related to many
diseases. There is a need to find new potential effective therapies for some skin conditions …

Significance: Cutaneous wound healing is a serious problem worldwide that affects patients
with various wound types, resulting from burns, traumatic injuries, and diabetes. Despite the …

The mechanisms underlying immunomodulatory ability of mesenchymal stromal cells
(MSCs) remain unknown. Recently, studies suggested that the immunomodulatory activity of …

Introduction This study was aimed at deciphering the secretome of adipose-derived
mesenchymal stromal cells (ADSCs) cultured in standard and hypoxic conditions to reveal …

Adipose-derived stem cells (ASCs) mainly exert their function by secreting materials that are
collectively termed the secretome. Despite recent attention to the secretome as an …

Purpose Most studies on immune tolerance of mesenchymal stem cells (MSCs) have been
performed using MSCs derived from bone marrow, cord blood, or adipose tissue. MSCs also …

Background Given the limitations of current therapies for the reconstruction of bone defects,
regenerative medicine has arisen as a new therapeutic strategy along with mesenchymal …

Background Chronic refractory wounds easily relapse and seriously affect the patients'
quality of life. Previous studies have shown that stromal vascular fraction gel (SVF-gel) …

The potential use of stem cell-based therapies for the repair and regeneration of various
tissues and organs offers a paradigm shift in regenerative medicine. The use of either …

Solid organ and composite tissue allotransplanation have been widely applied to treat end-
stage organ failure and massive tissue defects, respectively. Currently there are a lot of …