Antimicrobial resistance (AMR) is becoming one of the largest threats to public health
worldwide, with the opportunistic pathogen Escherichia coli playing a major role in the AMR …

Evolution is generally considered to be unpredictable because genetic variations are known
to occur randomly. However, remarkable patterns of repeated convergent evolution are …

Although strain tolerance to high product concentrations is a barrier to the economically
viable biomanufacturing of industrial chemicals, chemical tolerance mechanisms are often …

Independent populations often use the same phenotypic and genetic solutions to adapt to a
selective challenge, suggesting that evolution is surprisingly repeatable. This observation …

Adaptation through the fitness landscape may be influenced by the gene pool or expression
network. However, genetic factors that determine the contribution of beneficial mutations …