In vitro assays can be useful in determining biological mechanism and optimizing scaffold
parameters, however translation of the in vitro results to clinics is generally hard. Animal …

Advanced bone healing approaches included a wide range of biomaterials that mainly
mimic the composition, structure, and properties of bone extracellular matrix with osteogenic …

In the field of fracture healing it is essential to know the impacts of new materials. Fracture
healing of long bones is studied in various animal models and extrapolated for use in …

Aims Fractures are the result of fragile bone structures after trauma caused by direct or
indirect external impact or strong muscular contraction. Most fracture patients undergo …

Background aims Adipose tissue-derived mesenchymal stromal cells (MSCs) have a higher
capacity for proliferation and differentiation compared with other cell lineages. Although …

The novel synthetic peptide P17-BMP-2 could promote cell attachment and enhance
osteogenic capability. A composite, comprising nano-hydroxyapatite, collagen and poly (L …

Today marine-derived biologic scaffolds are popular due to their biocompatibility and high
regenerative potential. Previous studies prepared hydroxyapatite from cuttlebone, the …

The aim of the present study was to establish an experimental animal model of fracture
nonunion, and to investigate the changes in serum biomarker concentrations in fracture …

Objective Several animal models have been used in fracture healing and bone graft studies,
but hematological responses are seldom reported. Therefore, the present study reported the …

Objective-The present study was aimed to evaluate repair of a critical segmental defect of
rabbit femur using the rabbit's femoral defects repaired by Zeolite and Zeolite/Collagen …