Blood–Brain Barrier Breakdown in Alzheimer's Disease: Mechanisms and Targeted Strategies
AE Alkhalifa, NF Al-Ghraiybah, J Odum… - International Journal of …, 2023 - mdpi.com
The blood–brain barrier (BBB) is a unique and selective feature of the central nervous
system's vasculature. BBB dysfunction has been observed as an early sign of Alzheimer's …
system's vasculature. BBB dysfunction has been observed as an early sign of Alzheimer's …
Olea europaea L-derived secoiridoids: Beneficial health effects and potential therapeutic approaches
Over the years, health challenges have become increasingly complex and global and, at the
beginning of the 21st century, chronic diseases, including cardiovascular, neurological, and …
beginning of the 21st century, chronic diseases, including cardiovascular, neurological, and …
An Appraisal of the Oleocanthal-Rich Extra Virgin Olive Oil (EVOO) and Its Potential Anticancer and Neuroprotective Properties
R Infante, M Infante, D Pastore, F Pacifici… - International Journal of …, 2023 - mdpi.com
Dietary consumption of olive oil represents a key pillar of the Mediterranean diet, which has
been shown to exert beneficial effects on human health, such as the prevention of chronic …
been shown to exert beneficial effects on human health, such as the prevention of chronic …
Extra-Virgin Olive Oil in Alzheimer's Disease: A Comprehensive Review of Cellular, Animal, and Clinical Studies
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized
by several pathological hallmarks, including the deposition of amyloid-β (Aβ) plaques …
by several pathological hallmarks, including the deposition of amyloid-β (Aβ) plaques …
Neuroprotective Effects of Olive Oil: A Comprehensive Review of Antioxidant Properties
M Gonçalves, N Vale, P Silva - Antioxidants, 2024 - mdpi.com
Neurodegenerative diseases are a significant challenge to global healthcare, and oxidative
stress plays a crucial role in their development. This paper presents a comprehensive …
stress plays a crucial role in their development. This paper presents a comprehensive …
[HTML][HTML] Reactive Oxygen Species, a Potential Therapeutic Target for Vascular Dementia
AL White, GM Talkington, B Ouvrier, S Ismael… - Biomolecules, 2024 - mdpi.com
Vascular dementia (VaD) is a progressive neurodegenerative condition prevalent among
elderly adults marked by cognitive decline resulting from injured and/or improperly …
elderly adults marked by cognitive decline resulting from injured and/or improperly …
[HTML][HTML] Anti-Inflammatory and Neuroprotective Polyphenols Derived from the European Olive Tree, Olea europaea L., in Long COVID and Other Conditions Involving …
P Papadopoulou, A Polissidis, G Kythreoti… - International Journal of …, 2024 - mdpi.com
The European olive tree, Olea europaea L., and its polyphenols hold great therapeutic
potential to treat neuroinflammation and cognitive impairment. This review examines the …
potential to treat neuroinflammation and cognitive impairment. This review examines the …
Pathophysiological role of high mobility group box-1 signaling in neurodegenerative diseases
V Kumar, P Kumar - Inflammopharmacology, 2024 - Springer
Nucleocytoplasmic translocation of HMGB1 (high mobility group box-1) plays a significant
role in disease progression. Several methods contribute to the translocation of HMGB1 from …
role in disease progression. Several methods contribute to the translocation of HMGB1 from …
Oleocanthal Ameliorates Metabolic and Behavioral Phenotypes in a Mouse Model of Alzheimer's Disease
Aging is a major risk factor for Alzheimer's disease (AD). AD mouse models are frequently
used to assess pathology, behavior, and memory in AD research. While the pathological …
used to assess pathology, behavior, and memory in AD research. While the pathological …
A theoretical model of dietary lipid variance as the origin of primary ciliary dysfunction in preeclampsia
NR Hart - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Serving as the cell's key interface in communicating with the outside world, primary cilia
have emerged as an area of multidisciplinary research interest over the last 2 decades …
have emerged as an area of multidisciplinary research interest over the last 2 decades …