Biogenesis and regulation of the let-7 miRNAs and their functional implications
H Lee, S Han, CS Kwon, D Lee - Protein & cell, 2016 - academic.oup.com
The let-7 miRNA was one of the first miRNAs discovered in the nematode, Caenorhabditis
elegans, and its biological functions show a high level of evolutionary conservation from the …
elegans, and its biological functions show a high level of evolutionary conservation from the …
The functions of animal microRNAs
V Ambros - Nature, 2004 - nature.com
MicroRNAs (miRNAs) are small RNAs that regulate the expression of complementary
messenger RNAs. Hundreds of miRNA genes have been found in diverse animals, and …
messenger RNAs. Hundreds of miRNA genes have been found in diverse animals, and …
[HTML][HTML] MicroRNAs: genomics, biogenesis, mechanism, and function
DP Bartel - cell, 2004 - cell.com
MicroRNAs (miRNAs) are endogenous∼ 22 nt RNAs that can play important regulatory
roles in animals and plants by targeting mRNAs for cleavage or translational repression …
roles in animals and plants by targeting mRNAs for cleavage or translational repression …
Oncomirs—microRNAs with a role in cancer
A Esquela-Kerscher, FJ Slack - Nature reviews cancer, 2006 - nature.com
MicroRNAs (miRNAs) are an abundant class of small non-protein-coding RNAs that function
as negative gene regulators. They regulate diverse biological processes, and bioinformatic …
as negative gene regulators. They regulate diverse biological processes, and bioinformatic …
MicroRNAs: small RNAs with a big role in gene regulation
MicroRNAs are a family of small, non-coding RNAs that regulate gene expression in a
sequence-specific manner. The two founding members of the microRNA family were …
sequence-specific manner. The two founding members of the microRNA family were …
Biosynthesis, turnover, and functions of chitin in insects
KY Zhu, H Merzendorfer, W Zhang… - Annual review of …, 2016 - annualreviews.org
Chitin is a major component of the exoskeleton and the peritrophic matrix of insects. It forms
complex structures in association with different assortments of cuticle and peritrophic matrix …
complex structures in association with different assortments of cuticle and peritrophic matrix …
MicroRNA Targets in Drosophila
The recent discoveries of microRNAs (miRNAs) and characterization of the first few targets
of their gene products in Caenorhabditis elegans and Drosophila melanogaster have set the …
of their gene products in Caenorhabditis elegans and Drosophila melanogaster have set the …
A custom microarray platform for analysis of microRNA gene expression
JM Thomson, J Parker, CM Perou, SM Hammond - Nature methods, 2004 - nature.com
MicroRNAs are short, noncoding RNA transcripts that post-transcriptionally regulate gene
expression. Several hundred microRNA genes have been identified in Caenorhabditis …
expression. Several hundred microRNA genes have been identified in Caenorhabditis …
MicroRNA biogenesis: coordinated cropping and dicing
VN Kim - Nature reviews Molecular cell biology, 2005 - nature.com
The recent discovery of microRNAs (miRNAs) took many by surprise because of their
unorthodox features and widespread functions. These tiny,∼ 22-nucleotide, RNAs control …
unorthodox features and widespread functions. These tiny,∼ 22-nucleotide, RNAs control …
The let-7 family of microRNAs
S Roush, FJ Slack - Trends in cell biology, 2008 - cell.com
The first two known microRNAs (miRNAs), lin-4 and let-7, were originally discovered in the
nematode Caenorhabditis elegans and control the timing of stem-cell division and …
nematode Caenorhabditis elegans and control the timing of stem-cell division and …