Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications

YH Chung, H Cai, NF Steinmetz - Advanced Drug Delivery Reviews, 2020 - Elsevier
Viral nanoparticles (VNPs) encompass a diverse array of naturally occurring nanomaterials
derived from plant viruses, bacteriophages, and mammalian viruses. The application and …

The growing and glowing toolbox of fluorescent and photoactive proteins

EA Rodriguez, RE Campbell, JY Lin, MZ Lin… - Trends in biochemical …, 2017 - cell.com
Over the past 20 years, protein engineering has been extensively used to improve and
modify the fundamental properties of fluorescent proteins (FPs) with the goal of adapting …

Fluorescent proteins and their applications in imaging living cells and tissues

DM Chudakov, MV Matz, S Lukyanov… - Physiological …, 2010 - journals.physiology.org
Green fluorescent protein (GFP) from the jellyfish Aequorea victoria and its homologs from
diverse marine animals are widely used as universal genetically encoded fluorescent labels …

Blue-light receptors for optogenetics

A Losi, KH Gardner, A Möglich - Chemical reviews, 2018 - ACS Publications
Sensory photoreceptors underpin light-dependent adaptations of organismal physiology,
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …

Structure and function of plant photoreceptors

A Möglich, X Yang, RA Ayers… - Annual review of plant …, 2010 - annualreviews.org
Signaling photoreceptors use the information contained in the absorption of a photon to
modulate biological activity in plants and a wide range of organisms. The fundamental—and …

Small fluorescence-activating and absorption-shifting tag for tunable protein imaging in vivo

MA Plamont, E Billon-Denis, S Maurin… - Proceedings of the …, 2016 - National Acad Sciences
This paper presents Yellow Fluorescence-Activating and absorption-Shifting Tag (Y-FAST),
a small monomeric protein tag, half as large as the green fluorescent protein, enabling …

Imaging proteins inside cells with fluorescent tags

G Crivat, JW Taraska - Trends in biotechnology, 2012 - cell.com
Watching biological molecules provides clues to their function and regulation. Some of the
most powerful methods of labeling proteins for imaging use genetically encoded fluorescent …

LOV-based optogenetic devices: light-driven modules to impart photoregulated control of cellular signaling

A Pudasaini, KK El-Arab, BD Zoltowski - Frontiers in molecular …, 2015 - frontiersin.org
The Light-Oxygen-Voltage domain family of proteins is widespread in biology where they
impart sensory responses to signal transduction domains. The small, light responsive LOV …

Function, structure and mechanism of bacterial photosensory LOV proteins

J Herrou, S Crosson - Nature reviews microbiology, 2011 - nature.com
LOV (light, oxygen or voltage) domains are protein photosensors that are conserved in
bacteria, archaea, plants and fungi, and detect blue light via a flavin cofactor. LOV domains …

Genetically encoded fluorescent tags

K Thorn - Molecular biology of the cell, 2017 - Am Soc Cell Biol
Genetically encoded fluorescent tags are protein sequences that can be fused to a protein of
interest to render it fluorescent. These tags have revolutionized cell biology by allowing …