Gonadotropins are glycoprotein sex hormones regulating development and reproduction
and bind to specific G protein–coupled receptors expressed in the gonads. Their effects on …

Expression of the follicle-stimulating hormone receptor (FSHR), besides gonadal tissues,
has recently been detected in several extragonadal normal and tumorous tissues, including …

Abstract Background The Follicle Stimulating Hormone receptor (FSHR) is expressed by the
vascular endothelium in a wide range of human tumors. It was not determined however if …

Background Vascular endothelial growth factor (VEGF)-targeted therapy is the currently
standard treatment for advanced and metastatic renal cell carcinoma (RCC). Multiple …

Follicle stimulating hormone (FSH) and its receptor (FSHR) have been reported to be
responsible for several physiological functions and cancers. The responsiveness of stem …

Abstract Proteolysis Targeting Chimeras (PROTACs) based on multi-target inhibitors have
been reported several times recently. The advantages of PROTACs technology and the …

Recent treatment developments for metastatic renal cell carcinoma offer combinations of
immunotherapies or immunotherapy associated with tyrosine kinase inhibitors (TKI). There …

Epidemiological, clinical, biochemical and genetic research has revealed that renal cell
cancer (RCC) etiology is hormone-related. It was shown that hormone receptors are …

The cellular pathway of follicle-stimulating hormone (FSH) and its receptor (FSHR) is
typically involved in reproduction in mammals. In humans, the FSHR is normally found in …

Estrogen withdrawal in aging women contributes to the progression of chronic kidney
disease (CKD). However, the effect of high circulating follicle‐stimulating hormone (FSH) …