atherosclerosis, hypertension, cardiac hypertrophy and remodeling, angiogenesis and
collateral formation, stroke, and heart failure. In this review, we discuss in detail the …

Complex protein networks are involved in nearly all cellular processes. To uncover these
vast networks of protein interactions, various high-throughput screening technologies have …

The NADPH oxidase complex is involved in the destruction of phagocytosed pathogens
through the production of reactive oxygen species. This activatable complex consists of a …

Nox family NADPH oxidases serve a variety of functions requiring reactive oxygen species
(ROS) generation, including antimicrobial defense, biosynthetic processes, oxygen sensing …

Many proteins can be split into fragments that spontaneously reassemble, without covalent
linkage, into a functional protein. For split green fluorescent proteins (GFPs), fragment …

Professional phagocytes provide immunoprotection and aid in the maintenance of tissue
homeostasis. They perform these tasks by recognizing, engulfing and eliminating pathogens …

Studies of protein-protein interactions deep in organs and in whole mammals have been
hindered by a lack of genetically encoded fluorescent probes in near-infrared region for …

Cell-to-cell communication by exosomes controls normal and pathogenic processes,.
Viruses can spread in exosomes and thereby avoid immune recognition. While biogenesis …

Multiple host molecules are known to be involved in the cellular entry of filoviruses, including
Ebola virus (EBOV); T-cell immunoglobulin and mucin domain 1 (TIM-1) and Niemann-Pick …

The mechanisms that determine localized formation of reactive oxygen species (ROS)
through NADPH (reduced form of nicotinamide adenine dinucleotide phosphate) oxidase …