Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. It is
classified as familial and sporadic. The dominant familial or autosomal presentation …

Multifactorial diseases are characterized by inter-individual variation in etiology, age of
onset, and penetrance. These diseases tend to be relatively common and arise from the …

Reduction and oxidation reactions are essential for biochemical processes. They are part of
metabolic pathways and signal transduction. Reactive oxygen species (ROS) as second …

Decades of research have demonstrated an incontrovertible role of amyloid-β (Aβ) in the
etiology of Alzheimer's disease (AD). However, the overemphasis on the pathological …

Alzheimer's disease (AD) is the most common form of dementia that affects millions of
individuals worldwide. Although the research over the last decades has provided new …

Balanced synaptic inhibition, controlled by multiple synaptic adhesion proteins, is critical for
proper brain function. MDGA1 (meprin, A-5 protein, and receptor protein-tyrosine …

Alzheimer's disease (AD), a common form of dementia, is caused in part by the aggregation
and accumulation in the brain of amyloid β (Aβ), a product of the proteolytic cleavage of …

Alzheimer's disease (AD) represents a prominent neurodegenerative disorder (NDD),
accounting for the majority of dementia cases worldwide. In addition to memory deficits …

The diagnosis, treatment, and management of dementia provide significant challenges due
to its chronic cognitive impairment. The complexity of this condition is further highlighted by …

Background: In the past 10 years, significant progress has been made in understanding the
pathogenic chain of events that causes Alzheimer's disease (AD). According to the most …