Neuropathic pain is a frequent condition caused by a lesion or disease of the central or
peripheral somatosensory nervous system. A frequent cause of peripheral neuropathic pain …

Candidiasis has increased substantially worldwide over recent decades and is a significant
cause of morbidity and mortality, especially among critically ill patients. Diabetes mellitus …

Diabetes is a disease characterized by a relative or absolute lack of insulin, leading to
hyperglycaemia. There are two main types of diabetes: type 1 diabetes and type 2 diabetes …

Among the most widely used animal models in obesity-induced type 2 diabetes mellitus
(T2DM) research are the congenital leptin-and leptin receptor-deficient rodent models …

Pain is ultimately a perceptual phenomenon. It is built from information gathered by
specialized pain receptors in tissue, modified by spinal and supraspinal mechanisms, and …

Neuropathic pain is triggered by lesions to the somatosensory nervous system that alter its
structure and function so that pain occurs spontaneously and responses to noxious and …

Many are frustrated with the lack of translational progress in the pain field, in which huge
gains in basic science knowledge obtained using animal models have not led to the …

Neuropathy is the most common and debilitating complication of diabetes and results in
pain, decreased motility, and amputation. Diabetic neuropathy encompasses a variety of …

Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes and is
associated with significant morbidity and mortality. DPN is characterized by progressive …

Diabetic neuropathy is the most common complication of diabetes, affecting 50% of diabetic
patients. Currently, the only treatment for diabetic neuropathy is glucose control and careful …