Melanoma is the most lethal skin cancer that originates from the malignant transformation of
melanocytes. Although melanoma has long been regarded as a cancerous malignancy with …

Immune checkpoint blockage has been considered a breakthrough in cancer treatment,
achieving encouraging anti-tumor effects in some advanced solid malignancies. However …

Triptolide possesses the trait of renal protection. Epithelial-mesenchymal transition (EMT) is
closely linked to the pathogenesis of diabetic kidney disease (DKD). MicroRNAs have …

Ethnopharmacological relevance Oils and extracts of Eugenia uniflora have been reported
as antimicrobial, antifungal, antinociceptive, antiprotozoal, antioxidant and cytotoxic. Aim of …

Trop2 is considered to have an important function in tumor metastasis and the promotion of
epithelial‑mesenchymal transition (EMT). E‑cadherin is a crucial factor in intercellular …

Epithelial‐mesenchymal transition (EMT) is involved in physiologic processes such as
embryogenesis and wound healing. A similar mechanism occurs in some tumors where …

The extracellular matrix (ECM) is made up of noncellular components that have special
properties for influencing cell behavior and tissue structure. Small leucine-rich …

Most of the herbal origin drugs possess water insoluble active constituents which lower the
bioavailability and increase systemic clearance after administration of repeated or higher …

Melanoma is one of the deadliest skin tumors, accounting for almost 90% of skin cancer
mortality. Although immune therapy and targeted therapy have dramatically changed the …

Introduction Previous studies have indicated that the small leucine-rich proteoglycan (SLR)
osteoglycin (OGN) is downregulated in various cancers, including squamous cervical …