Chronic adipose tissue inflammation linking obesity to insulin resistance and type 2 diabetes
Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …
[HTML][HTML] Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus
MS Burhans, DK Hagman, JN Kuzma… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …
Metabolic adaptation and maladaptation in adipose tissue
ET Chouchani, S Kajimura - Nature metabolism, 2019 - nature.com
Adipose tissue possesses the remarkable capacity to control its size and function in
response to a variety of internal and external cues, such as nutritional status and …
response to a variety of internal and external cues, such as nutritional status and …
Mitochondrial dysfunction in obesity
AH de Mello, AB Costa, JDG Engel, GT Rezin - Life sciences, 2018 - Elsevier
Obesity leads to various changes in the body. Among them, the existing inflammatory
process may lead to an increase in the production of reactive oxygen species (ROS) and …
process may lead to an increase in the production of reactive oxygen species (ROS) and …
Adipose tissue macrophage populations and inflammation are associated with systemic inflammation and insulin resistance in obesity
Obesity is accompanied by numerous systemic and tissue-specific derangements, including
systemic inflammation, insulin resistance, and mitochondrial abnormalities in skeletal …
systemic inflammation, insulin resistance, and mitochondrial abnormalities in skeletal …
The influence of oxidative stress on thyroid diseases
J Kochman, K Jakubczyk, P Bargiel, K Janda-Milczarek - Antioxidants, 2021 - mdpi.com
Thyroid diseases, including neoplasms, autoimmune diseases and thyroid dysfunctions, are
becoming a serious social problem with rapidly increasing prevalence. The latter is …
becoming a serious social problem with rapidly increasing prevalence. The latter is …
Mitochondria: diversity in the regulation of the NLRP3 inflammasome
Recent studies have identified new roles for mitochondria in the regulation of
autoinflammatory processes. Emerging data suggests that the release of danger signals …
autoinflammatory processes. Emerging data suggests that the release of danger signals …
Impaired mitochondrial biogenesis in adipose tissue in acquired obesity
S Heinonen, J Buzkova, M Muniandy, R Kaksonen… - Diabetes, 2015 - Am Diabetes Assoc
Low mitochondrial number and activity have been suggested as underlying factors in
obesity, type 2 diabetes, and metabolic syndrome. However, the stage at which …
obesity, type 2 diabetes, and metabolic syndrome. However, the stage at which …
Fat cell size: measurement methods, pathophysiological origins, and relationships with metabolic dysregulations
The obesity pandemic increasingly causes morbidity and mortality from type 2 diabetes,
cardiovascular diseases and many other chronic diseases. Fat cell size (FCS) predicts …
cardiovascular diseases and many other chronic diseases. Fat cell size (FCS) predicts …
Mitochondria in white, brown, and beige adipocytes
M Cedikova, M Kripnerová, J Dvorakova… - Stem cells …, 2016 - Wiley Online Library
Mitochondria play a key role in energy metabolism in many tissues, including cardiac and
skeletal muscle, brain, liver, and adipose tissue. Three types of adipose depots can be …
skeletal muscle, brain, liver, and adipose tissue. Three types of adipose depots can be …