Exposures, mechanisms, and impacts of endocrine-active flame retardants

LV Dishaw, LJ Macaulay, SC Roberts… - Current opinion in …, 2014 - Elsevier
Highlights•Widespread exposure to flame retardants occurs in indoor environments.•Indoor
exposure is associated with body burdens.•Highest human exposures occur in early …

Environment and human exposure to persistent organic pollutants (POPs) in India: A systematic review of recent and historical data

BM Sharma, GK Bharat, S Tayal, L Nizzetto… - Environment …, 2014 - Elsevier
Persistent organic pollutants (POPs) have been used in a wide range of agricultural and
industrial commodities, resulting in vigorous deterioration of environment and human health …

Is the PentaBDE replacement, tris (1, 3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells

LV Dishaw, CM Powers, IT Ryde, SC Roberts… - Toxicology and applied …, 2011 - Elsevier
Organophosphate flame retardants (OPFRs) are used as replacements for the commercial
PentaBDE mixture that was phased out in 2004. OPFRs are ubiquitous in the environment …

Associations between polybrominated diphenyl ether (PBDE) flame retardants, phenolic metabolites, and thyroid hormones during pregnancy

HM Stapleton, S Eagle, R Anthopolos… - Environmental …, 2011 - ehp.niehs.nih.gov
Background: Polybrominated diphenyl ethers (PBDEs) are chemical additives used as flame
retardants in commercial products. PBDEs are bioaccumulative and persistent and have …

Hormone Activity of Hydroxylated Polybrominated Diphenyl Ethers on Human Thyroid Receptor-β: In Vitro and In Silico Investigations

F Li, Q Xie, X Li, N Li, P Chi, J Chen… - Environmental health …, 2010 - ehp.niehs.nih.gov
Background Hydroxylated polybrominated diphenyl ethers (HO-PBDEs) may disrupt thyroid
hormone status because of their structural similarity to thyroid hormone. However, the …

Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese …

H Kojima, S Takeuchi, N Uramaru… - Environmental …, 2009 - ehp.niehs.nih.gov
Background An increasing number of studies are reporting the existence of polybrominated
diphenyl ethers (PBDEs) and their hydroxylated (HO) and methoxylated (MeO) metabolites …

Metabolism of Polybrominated Diphenyl Ethers (PBDEs) by Human Hepatocytes in Vitro

HM Stapleton, SM Kelly, R Pei… - Environmental health …, 2009 - ehp.niehs.nih.gov
Background Polybrominated diphenyl ethers (PBDEs) are flame-retardant chemicals that
accumulate in human tissues and are potential toxicants. Concentrations of PBDEs in …

Polybrominated diphenyl ethers (PBDEs) and bioaccumulative hydroxylated PBDE metabolites in young humans from Managua, Nicaragua

M Athanasiadou, SN Cuadra, G Marsh… - Environmental …, 2008 - ehp.niehs.nih.gov
Objective Our aim was to investigate exposure to polybrominated diphenyl ethers (PBDEs)
in a young urban population in a developing country, with focus on potentially highly …

Origin of hydroxylated brominated diphenyl ethers: natural compounds or man-made flame retardants?

Y Wan, S Wiseman, H Chang, X Zhang… - … science & technology, 2009 - ACS Publications
Polybrominated diphenyl ethers (PBDEs) have been widely used as flame retardants. The
structurally related hydroxylated PBDEs (OH-PBDEs) and methoxylated PBDEs (MeO …

Polybrominated diphenyl ethers and their hydroxylated/methoxylated analogs: environmental sources, metabolic relationships, and relative toxicities

SB Wiseman, Y Wan, H Chang, X Zhang… - Marine pollution …, 2011 - Elsevier
Brominated compounds are ubiquitous in the aquatic environment. The polybrominated
diphenyl ether (PBDE) flame retardants are anthropogenic compounds of concern. Studies …