Accurate diagnosis, monitoring and treatment decisions in patients with chronic liver disease
currently rely on biopsy as the diagnostic gold standard, and this has constrained early …

Cardiometabolic disease refers to the spectrum of chronic conditions that include diabetes,
hypertension, atheromatosis, non-alcoholic fatty liver disease, and their long-term impact on …

Background The liver R2* value is widely used as a measure of liver iron but may be
confounded by the presence of hepatic steatosis and other covariates. Purpose To identify …

Background Liver iron content (LIC) in chronic liver disease (CLD) is currently determined by
performing an invasive liver biopsy. MRI using R2* relaxometry is a noninvasive alternative …

Background Magnetic resonance elastography (MRE) can determine the presence and
stage of liver fibrosis. Data on normative MRE values, while reported in adults, are limited in …

Purpose To evaluate the precision profile (repeatability and reproducibility) of quantitative
STEAM‐MRS and to determine the relationships between multiple MR biomarkers of chronic …

Background Hepatic iron content (HIC) is an important parameter for the management of
iron overload. Non‐invasive HIC assessment is often performed using biopsy‐calibrated two …

Purpose To evaluate if single-voxel MR spectroscopy (MRS) of iron and fat correlates with
biopsy results of hepatic steatosis and iron overload, and to compare MR-measurements …

The purpose of this work was to investigate sources of bias in magnetic resonance imaging
(MRI) liver fat quantification that lead to a dependence of the proton density fat fraction …

Chemical‐shift‐based fat‐water MRI signal models with single‐or dual‐R2* correction have
been proposed for quantification of fat fraction (FF) and assessment of hepatic steatosis …