Raman techniques: fundamentals and frontiers

RR Jones, DC Hooper, L Zhang, D Wolverson… - Nanoscale research …, 2019 - Springer
Driven by applications in chemical sensing, biological imaging and material
characterisation, Raman spectroscopies are attracting growing interest from a variety of …

Raman spectroscopy: techniques and applications in the life sciences

DW Shipp, F Sinjab, I Notingher - Advances in Optics and Photonics, 2017 - opg.optica.org
Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …

Coherent anti-Stokes Raman scattering microscopy: chemical imaging for biology and medicine

CL Evans, XS Xie - Annu. Rev. Anal. Chem., 2008 - annualreviews.org
Coherent anti-Stokes Raman scattering (CARS) microscopy is a label-free imaging
technique that is capable of real-time, nonperturbative examination of living cells and …

Single cell optical imaging and spectroscopy

AS Stender, K Marchuk, C Liu, S Sander… - Chemical …, 2013 - ACS Publications
In his 1665 treatise, Micrographia, Robert Hooke described the many observations he had
made using a microscope, including compartment-like structures in cork samples that he …

Chemical contrast for imaging living systems: molecular vibrations drive CARS microscopy

JP Pezacki, JA Blake, DC Danielson… - Nature chemical …, 2011 - nature.com
Cellular biomolecules contain unique molecular vibrations that can be visualized by
coherent anti-Stokes Raman scattering (CARS) microscopy without the need for labels. Here …

Quantitative label-free imaging of lipid composition and packing of individual cellular lipid droplets using multiplex CARS microscopy

HA Rinia, KNJ Burger, M Bonn, M Müller - Biophysical journal, 2008 - cell.com
Lipid droplets (LDs) are highly dynamic organelles that perform multiple functions, including
the regulated storage and release of cholesterol and fatty acids. Information on the …

Chemical analysis in vivo and in vitro by Raman spectroscopy—from single cells to humans

S Wachsmann-Hogiu, T Weeks, T Huser - Current opinion in biotechnology, 2009 - Elsevier
The gold standard for clinical diagnostics of tissues is immunofluorescence staining. Toxicity
of many fluorescent dyes precludes their application in vivo. Raman spectroscopy, a …

Optimally chirped multimodal CARS microscopy based on a single Ti: sapphire oscillator

AF Pegoraro, A Ridsdale, DJ Moffatt, Y Jia… - Optics express, 2009 - opg.optica.org
We demonstrate high performance coherent anti-Stokes Raman scattering (CARS)
microscopy of live cells and tissues with user-variable spectral resolution and broad Raman …

Coherent anti-Stokes Raman scattering: Spectroscopy and microscopy

F El-Diasty - Vibrational Spectroscopy, 2011 - Elsevier
In this review the basis, recent developments and applications of coherent anti-Stokes
Raman scattering (CARS) in the fields of spectroscopy and microscopy are dialed with. The …

Adaptive optics for enhanced signal in CARS microscopy

AJ Wright, SP Poland, JM Girkin, CW Freudiger… - Optics express, 2007 - opg.optica.org
We report the use of adaptive optics with coherent anti-Stokes Raman scattering (CARS)
microscopy for label-free deep tissue imaging based on molecular vibrational spectroscopy …