Specialized pro-resolving mediator network: an update on production and actions

N Chiang, CN Serhan - Essays in Biochemistry, 2020 - portlandpress.com
Today, persistent and uncontrolled inflammation is appreciated to play a pivotal role in many
diseases, such as cardiovascular diseases, neurodegenerative diseases, metabolic …

Resolution of inflammation: An organizing principle in biology and medicine

D Panigrahy, MM Gilligan, CN Serhan… - Pharmacology & …, 2021 - Elsevier
The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …

[HTML][HTML] Inflammation-mediated tissue damage in pulmonary tuberculosis and host-directed therapeutic strategies

D Tiwari, AR Martineau - Seminars in Immunology, 2023 - Elsevier
Abstract Treatment of tuberculosis (TB) involves the administration of anti-mycobacterial
drugs for several months. The emergence of drug-resistant strains of Mycobacterium …

Resolvins and cysteinyl-containing pro-resolving mediators activate resolution of infectious inflammation and tissue regeneration

CN Serhan, N Chiang - Prostaglandins & other lipid mediators, 2023 - Elsevier
This review is a synopsis of the main points from the opening presentation by the authors in
the Resolution of Inflammation session at the 8th European Workshop on Lipid Mediators …

Role of specialized pro-resolving lipid mediators in pulmonary inflammation diseases: Mechanisms and development

A Yang, Y Wu, G Yu, H Wang - Respiratory Research, 2021 - Springer
Inflammation is an essential mechanism of various diseases. The development and
resolution of inflammation are complex immune-modulation processes which induce the …

Specialized Pro-Resolving Lipid Mediators: Endogenous Roles and Pharmacological Activities in Infections

FS Rasquel-Oliveira, MDV Silva, G Martelossi-Cebinelli… - Molecules, 2023 - mdpi.com
During an infection, inflammation mobilizes immune cells to eliminate the pathogen and
protect the host. However, inflammation can be detrimental when exacerbated and/or …

Specialized pro‐resolving mediators: biosynthesis and biological role in bacterial infections

PM Jordan, O Werz - The FEBS journal, 2022 - Wiley Online Library
Acute inflammation caused by bacterial infections is an essential biological defence
mechanism of the host in order to neutralize and clear the invaders and to return to …

Multimodal plasma metabolomics and lipidomics in elucidating metabolic perturbations in tuberculosis patients with concurrent type 2 diabetes

NTH Yen, NK Anh, RP Jayanti, NK Phat, DH Vu… - Biochimie, 2023 - Elsevier
Type 2 diabetes mellitus (DM) poses a major burden for the treatment and control of
tuberculosis (TB). Characterization of the underlying metabolic perturbations in DM patients …

Oxidative stress and inflammatory mediators in exhaled breath condensate of patients with pulmonary tuberculosis. A pilot study with a biomarker perspective

S Guzmán-Beltrán, LE Carreto-Binaghi, C Carranza… - Antioxidants, 2021 - mdpi.com
Tuberculosis (TB) is one of the highest infectious burdens worldwide. An excess of
inflammation and inadequate antioxidant defense mechanisms are believed to lead to …

Pathogenicity of Type I Interferons in Mycobacterium tuberculosis

A Mundra, A Yegiazaryan, H Karsian, D Alsaigh… - International Journal of …, 2023 - mdpi.com
Tuberculosis (TB) is a leading cause of mortality due to infectious disease and rates have
increased during the emergence of COVID-19, but many of the factors determining disease …