Role of lipid accumulation and inflammation in atherosclerosis: focus on molecular and cellular mechanisms

K Malekmohammad, EE Bezsonov… - Frontiers in …, 2021 - frontiersin.org
Atherosclerosis is a chronic lipid-driven and maladaptive inflammatory disease of arterial
intima. It is characterized by the dysfunction of lipid homeostasis and signaling pathways …

The link between diabetes and atherosclerosis

L La Sala, F Prattichizzo… - European journal of …, 2019 - journals.sagepub.com
Atherosclerosis is one of the main complications of diabetes involving multiple causative
factors. Dysfunction of the vascular endothelium is a hallmark of most conditions that are …

Novel insights into the molecular mechanisms of atherosclerosis

A Wojtasińska, W Frąk, W Lisińska, N Sapeda… - International journal of …, 2023 - mdpi.com
Atherosclerosis is one of the most fatal diseases in the world. The associated thickening of
the arterial wall and its background and consequences make it a very composite disease …

Noncoding RNAs in vascular diseases

N Jaé, S Dimmeler - Circulation research, 2020 - Am Heart Assoc
The advent of deep sequencing technologies led to the identification of a considerable
amount of noncoding RNA transcripts, which are increasingly recognized for their functions …

Effect of endothelial progenitor cell-derived extracellular vesicles on endothelial cell ferroptosis and atherosclerotic vascular endothelial injury

L Li, H Wang, J Zhang, X Chen, Z Zhang, Q Li - Cell death discovery, 2021 - nature.com
Atherosclerosis (AS) is a chronic inflammatory disorder characterized by endothelial
dysfunction. Endothelial progenitor cells (EPCs) can overcome endothelial dysfunction and …

Targeting immune senescence in atherosclerosis

DM Vellasamy, SJ Lee, KW Goh, BH Goh… - International Journal of …, 2022 - mdpi.com
Atherosclerosis is one of the main underlying causes of cardiovascular diseases (CVD). It is
associated with chronic inflammation and intimal thickening as well as the involvement of …

The role of smooth muscle cells in plaque stability: Therapeutic targeting potential

JL Harman, HF Jørgensen - British journal of pharmacology, 2019 - Wiley Online Library
Events responsible for cardiovascular mortality and morbidity are predominantly caused by
rupture of “vulnerable” atherosclerotic lesions. Vascular smooth muscle cells (VSMCs) play …

Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation …

T Kiss, CB Giles, S Tarantini, A Yabluchanskiy… - Geroscience, 2019 - Springer
Understanding molecular mechanisms involved in vascular aging is essential to develop
novel interventional strategies for treatment and prevention of age-related vascular …

Atherosclerosis and its related laboratory biomarkers

V Della Corte, F Todaro, M Cataldi… - International Journal of …, 2023 - mdpi.com
Atherosclerosis constitutes a persistent inflammatory ailment, serving as the predominant
underlying condition for coronary artery disease (CAD), peripheral artery disease (PAD) …

Platelets as therapeutic targets to prevent atherosclerosis

H Nording, L Baron, HF Langer - Atherosclerosis, 2020 - Elsevier
Cardiovascular disease remains the main cause of death worldwide. For this reason,
strategies for the primary prevention of atherosclerosis and atherosclerosis-related …