Coronaviruses (CoVs) are a group of enveloped, single-stranded positive genomic RNA
viruses and some of them are known to cause severe respiratory diseases in human …

We are living through an unprecedented crisis with the rapid spread of the new coronavirus
disease (COVID-19) worldwide within a short time. The timely availability of thousands of …

Macroautophagy/autophagy is an evolutionarily conserved pathway responsible for clearing
cytosolic aggregated proteins, damaged organelles or invading microorganisms …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Autophagy as a means of cell killing was first advanced by Clark's phenotypic description of
'Type II autophagic cell death'in 1990. However, this phenomenon later came into question …

Autophagy is the major intracellular degradation system by which cytoplasmic materials are
delivered to and degraded in the lysosome. However, the purpose of autophagy is not the …

Autophagy is an essential, conserved lysosomal degradation pathway that controls the
quality of the cytoplasm by eliminating protein aggregates and damaged organelles. It …

Autophagy (also known as macroautophagy) captures intracellular components in
autophagosomes and delivers them to lysosomes, where they are degraded and recycled …

Many tumors become addicted to autophagy for survival, suggesting inhibition of autophagy
as a potential broadly applicable cancer therapy. ULK1/Atg1 is the only serine/threonine …

Mitochondria are essential organelles that regulate cellular energy homeostasis and cell
death. The removal of damaged mitochondria through autophagy, a process called …