Carcinogenesis: Failure of resolution of inflammation?
A Fishbein, BD Hammock, CN Serhan… - Pharmacology & …, 2021 - Elsevier
Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …
key characteristic of carcinogens. However, the failure of resolution of inflammation in …
Inflammatory auxo-action in the stem cell division theory of cancer
Y Luo, JH Xiao - PeerJ, 2023 - peerj.com
Acute inflammation is a beneficial response to the changes caused by pathogens or injuries
that can eliminate the source of damage and restore homeostasis in damaged tissues …
that can eliminate the source of damage and restore homeostasis in damaged tissues …
Vinpocetine mitigates DMH-induce pre-neoplastic colon damage in rats through inhibition of pro-inflammatory cytokines
Colorectal cancer (CRC) is currently recognized as the third most prevalent cancer
worldwide. Vinpocetine is a synthetic derivative of the vinca alkaloid vincamine. It has been …
worldwide. Vinpocetine is a synthetic derivative of the vinca alkaloid vincamine. It has been …
Poly(lactic-co-glycolic acid)-loaded nanoparticles of betulinic acid for improved treatment of hepatic cancer: characterization, in vitro and in vivo evaluations
Purpose The application of betulinic acid (B), a potent antineoplastic agent, is limited due to
poor bioavailability, short plasma half-life and inappropriate tissue distribution. Thus, we …
poor bioavailability, short plasma half-life and inappropriate tissue distribution. Thus, we …
Assessments of in vitro and in vivo antineoplastic potentials of β-sitosterol-loaded PEGylated niosomes against hepatocellular carcinoma
Abstract β-sitosterol (BS), a phytosterol, exhibits ameliorative effects on hepatocellular
carcinoma (HCC) due to its antioxidant activities. However, its poor aqueous solubility and …
carcinoma (HCC) due to its antioxidant activities. However, its poor aqueous solubility and …
Preclinical Evaluation of Dimethyl Itaconate Against Hepatocellular Carcinoma via Activation of the e/iNOS-Mediated NF-κB–Dependent Apoptotic Pathway
Hepatocellular carcinoma (HCC) is one of the most common tumors affecting a large
population worldwide, with the fifth and seventh greatest mortality rates among men and …
population worldwide, with the fifth and seventh greatest mortality rates among men and …
The pharmacological effect of apricot seeds extracts and amygdalin in experimentally induced liver damage and hepatocellular carcinoma
A Ramadan, G Kamel, NE Awad… - Journal of …, 2020 - herbmedpharmacol.com
Abstract Introduction: Apricot (Prunus armeniaca L.) has been widely used for the treatment
of several disorders such as liver diseases, but the hepatoprotective and anticancer …
of several disorders such as liver diseases, but the hepatoprotective and anticancer …
Pentapeptide cRGDfK-Surface Engineered Nanostructured Lipid Carriers as an Efficient Tool for Targeted Delivery of Tyrosine Kinase Inhibitor for Battling …
Background Antitumor research aims to efficiently target hepatocarcinoma cells (HCC) for
drug delivery. Nanostructured lipid carriers (NLCs) are promising for active tumour targeting …
drug delivery. Nanostructured lipid carriers (NLCs) are promising for active tumour targeting …
Antiproliferative, apoptotic and anti-inflammatory potential of 5H-benzo [h] thiazolo [2, 3-b] quinazoline analogues: Novel series of anticancer compounds
Lung cancer (LC) is the most common cancer in males. As per GLOBOCAN 2020, 8.1% of
deaths and 5.9% of cases of LC were reported in India. Our laboratory has previously …
deaths and 5.9% of cases of LC were reported in India. Our laboratory has previously …
Antineoplastic properties of zafirlukast against hepatocellular carcinoma via activation of mitochondrial mediated apoptosis
P Kumar, A Agarwal, AK Singh, AK Gautam… - Regulatory toxicology …, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwideand
haslimited treatment options. In view of this, zafirlukast (ZAF) was administered orally to DEN …
haslimited treatment options. In view of this, zafirlukast (ZAF) was administered orally to DEN …