From first-passage times of random walks in confinement to geometry-controlled kinetics

O Bénichou, R Voituriez - Physics Reports, 2014 - Elsevier
We present a general theory which allows one to accurately evaluate the mean first-passage
time (FPT) for regular random walks in bounded domains, and its extensions to related first …

Hybrid asymptotic-numerical approach for estimating first-passage-time densities of the two-dimensional narrow capture problem

AE Lindsay, RT Spoonmore, JC Tzou - Physical Review E, 2016 - APS
A hybrid asymptotic-numerical method is presented for obtaining an asymptotic estimate for
the full probability distribution of capture times of a random walker by multiple small traps …

First passage statistics for the capture of a Brownian particle by a structured spherical target with multiple surface traps

AE Lindsay, AJ Bernoff, MJ Ward - Multiscale Modeling & Simulation, 2017 - SIAM
We study the first passage time problem for a diffusing molecule in an enclosed region to hit
a small spherical target whose surface contains many small absorbing traps. This study is …

Escape from subcellular domains with randomly switching boundaries

PC Bressloff, SD Lawley - Multiscale Modeling & Simulation, 2015 - SIAM
Motivated by various cellular transport processes, we consider diffusion in a potential and
analyze the escape time to boundaries that randomly switch between absorbing and …

Conditional mean first passage times to small traps in a 3-D domain with a sticky boundary: applications to T cell searching behavior in lymph nodes

MI Delgado, MJ Ward, D Coombs - Multiscale Modeling & Simulation, 2015 - SIAM
Calculating the time required for a diffusing object to reach a small target within a larger
domain is a feature of a large class of modeling and simulation efforts in biology. Here, we …

Extended narrow escape with many windows for analyzing viral entry into the cell nucleus

T Lagache, D Holcman - Journal of Statistical Physics, 2017 - Springer
Many viruses must enter the cell nucleus through small nanopores in order to replicate. We
model here the viral motion as a stochastic process described by the Survival Fokker …

An iterative procedure for finding locally and globally optimal arrangements of particles on the unit sphere

WJM Ridgway, AF Cheviakov - Computer Physics Communications, 2018 - Elsevier
The problem of determination of globally optimal arrangements of N pairwise-interacting
particles arises in a variety of biological, physical, and chemical applications. At the same …

Asymptotic analysis of narrow escape problems in nonspherical three-dimensional domains

D Gomez, AF Cheviakov - Physical Review E, 2015 - APS
Narrow escape problems consider the calculation of the mean first passage time (MFPT) for
a particle undergoing Brownian motion in a domain with a boundary that is everywhere …

Brownian dynamics simulations for the narrow escape problem in the unit sphere

V Srivastava, A Cheviakov - Physical Review E, 2021 - APS
The narrow escape problem is a first-passage problem that concerns the calculation of the
time needed for a Brownian particle to leave a domain with localized absorbing boundary …

Counterexample to the Lévy flight foraging hypothesis in the narrow capture framework

JC Tzou, L Tzou - Physical Review Research, 2024 - APS
The Lévy flight foraging hypothesis asserts that biological organisms have evolved to
employ (truncated) Lévy flight searches due to such strategies being more efficient than …