Runs of homozygosity: current knowledge and applications in livestock
E Peripolli, DP Munari, M Silva, ALF Lima… - Animal …, 2017 - Wiley Online Library
This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …
Genomics advances the study of inbreeding depression in the wild
Inbreeding depression (reduced fitness of individuals with related parents) has long been a
major focus of ecology, evolution, and conservation biology. Despite decades of research …
major focus of ecology, evolution, and conservation biology. Despite decades of research …
How to study runs of homozygosity using PLINK? A guide for analyzing medium density SNP data in livestock and pet species
R Meyermans, W Gorssen, N Buys, S Janssens - BMC genomics, 2020 - Springer
Background PLINK is probably the most used program for analyzing SNP genotypes and
runs of homozygosity (ROH), both in human and in animal populations. The last decade …
runs of homozygosity (ROH), both in human and in animal populations. The last decade …
Inbreeding and runs of homozygosity before and after genomic selection in North American Holstein cattle
Background While autozygosity as a consequence of selection is well understood, there is
limited information on the ability of different methods to measure true inbreeding. In the …
limited information on the ability of different methods to measure true inbreeding. In the …
Selection signatures in livestock genome: A review of concepts, approaches and applications
Livestock populations have been consistently improving in terms of performance and
productivity by selective breeding over the centuries. These selection strategies are …
productivity by selective breeding over the centuries. These selection strategies are …
A publicly available repository of ROH islands reveals signatures of selection in different livestock and pet species
W Gorssen, R Meyermans, S Janssens… - Genetics Selection …, 2021 - Springer
Background Runs of homozygosity (ROH) have become the state-of-the-art method for
analysis of inbreeding in animal populations. Moreover, ROH are suited to detect signatures …
analysis of inbreeding in animal populations. Moreover, ROH are suited to detect signatures …
From molecules to populations: appreciating and estimating recombination rate variation
JV Peñalba, JBW Wolf - Nature Reviews Genetics, 2020 - nature.com
Recombination is a central biological process with implications for many areas in the life
sciences. Yet we are only beginning to appreciate variation in the recombination rate along …
sciences. Yet we are only beginning to appreciate variation in the recombination rate along …
Genomic insights into the conservation status of the world's last remaining Sumatran rhinoceros populations
Small populations are often exposed to high inbreeding and mutational load that can
increase the risk of extinction. The Sumatran rhinoceros was widespread in Southeast Asia …
increase the risk of extinction. The Sumatran rhinoceros was widespread in Southeast Asia …
Population dynamics of Baltic herring since the Viking Age revealed by ancient DNA and genomics
LM Atmore, L Martínez-García… - Proceedings of the …, 2022 - National Acad Sciences
The world's oceans are currently facing major stressors in the form of overexploitation and
anthropogenic climate change. The Baltic Sea was home to the first “industrial” fishery∼ 800 …
anthropogenic climate change. The Baltic Sea was home to the first “industrial” fishery∼ 800 …
Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal
MA Stoffel, SE Johnston, JG Pilkington… - Nature …, 2021 - nature.com
Inbreeding depression is ubiquitous, but we still know little about its genetic architecture and
precise effects in wild populations. Here, we combine long-term life-history data with 417 K …
precise effects in wild populations. Here, we combine long-term life-history data with 417 K …