Lupus Nephritis: New and Emerging Biologic and Targeted Therapies

A Kale, M Lech, HJ Anders, AB Gaikwad - BioDrugs, 2023 - Springer
Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE), a
polyclonal systemic autoimmunity directed against nuclear and other self-antigens. SLE/LN …

Multidisciplinary approach to lupus nephritis: Clinical pearls, pitfalls, and positioning of newly-approved agents

A Fanouriakis, G Bertsias, G Liapis, S Marinaki… - Lupus, 2023 - journals.sagepub.com
Lupus nephritis (LN) is a major course of morbidity and mortality in patients with systemic
lupus erythematosus (SLE), best managed by a multidisciplinary group. To this end, we …

Is per-protocol kidney biopsy required in lupus nephritis?

I Parodis, G Moroni, M Calatroni, E Bellis, M Gatto - Autoimmunity Reviews, 2024 - Elsevier
Baseline kidney biopsy is recommended in lupus nephritis (LN). Biopsy allows to classify
different forms of LN and differentiate other forms of renal involvement, such as tubulo …

[HTML][HTML] Lupus Nephritis: Redefining the treatment goals

AS De Vriese, S Sethi, FC Fervenza - Kidney International, 2024 - Elsevier
The course of proliferative lupus nephritis is characterized by flares of activity alternating
with periods of quiescence against a background of chronic immune dysregulation. An …

Lupus nephritis: improving treatment options

M Kostopoulou, S Pitsigavdaki, G Bertsias - Drugs, 2022 - Springer
Despite improvements in patient and renal death rates following the introduction of potent
immunosuppressive drugs in earlier decades, a sizeable fraction of patients with lupus …

Tailored treatment strategies and future directions in systemic lupus erythematosus

D Nikolopoulos, L Fotis, O Gioti… - Rheumatology …, 2022 - Springer
Systemic lupus erythematosus (SLE) represents a diagnostic and therapeutic challenge for
physicians due to its protean manifestations and unpredictable course. The disease may …

[HTML][HTML] Consensus document of the Spanish Group for the Study of the Glomerular Diseases (GLOSEN) for the diagnosis and treatment of lupus nephritis

JE Rojas-Rivera, C García-Carro, AI Ávila… - Nefrología (English …, 2023 - Elsevier
A significant number of patients with systemic lupus erythematosus (between 20% and 60%
according to different reported series) develop lupus nephritis in the course of its evolution …

Impact of glucocorticoid dose on complete response, serious infections, and mortality during the initial therapy of lupus nephritis: A systematic review and meta …

G Figueroa‐Parra, MC Cuéllar‐Gutiérrez… - Arthritis & …, 2024 - Wiley Online Library
Objective To evaluate the effect of glucocorticoid regimens on renal response, infections,
and mortality among patients with lupus nephritis (LN). Methods We performed a systematic …

[HTML][HTML] Documento de consenso del Grupo de Estudio de Enfermedades Glomerulares de la Sociedad Española de Nefrología (GLOSEN) para el diagnóstico y …

JE Rojas-Rivera, C García-Carro, AI Ávila, M Espino… - nefrologia, 2023 - Elsevier
Un número importante de pacientes con lupus eritematoso sistémico (entre 20 a 60%,
según diferentes series) desarrolla nefritis lúpica en el curso de su evolución, lo que influye …

Real-world treatment utilization and economic implications of lupus nephritis disease activity in the United States

M Dall'Era, K Kalunian, M Eaddy, A Ogbonnaya… - Journal of Managed …, 2023 - jmcp.org
BACKGROUND: Lupus nephritis (LN) is a common and severe complication of systemic
lupus erythematosus (SLE), with approximately 40% of patients with SLE developing LN …