Spike timing–dependent plasticity (STDP) as a Hebbian synaptic learning rule has been
demonstrated in various neural circuits over a wide spectrum of species, from insects to …

Abstract Information theory has long been used to quantify interactions between two
variables. With the rise of complex systems research, multivariate information measures …

A major goal of neuroscience is to elucidate mechanisms of cortical information processing
and storage. Previous work from our laboratory revealed that propagation of local field …

At specific stages of development, nerve and muscle cells generate spontaneous electrical
activity that is required for normal maturation of intrinsic excitability and synaptic connectivity …

The visual cortex is organized into retinotopic maps that preserve an orderly representation
of the visual world, achieved by topographically precise inputs from the lateral geniculate …

Most neuronal networks, even in the absence of external stimuli, produce spontaneous
bursts of spikes separated by periods of reduced activity. The origin and functional role of …

A characteristic feature of sensory circuits is the existence of orderly connections that
represent maps of sensory space. A major research focus in developmental neurobiology is …

Patterned spontaneous activity in the developing retina is necessary to drive synaptic
refinement in the lateral geniculate nucleus (LGN). Using perforated patch recordings from …

Neuronal pentraxins (NPs) define a family of proteins that are homologous to C-reactive and
acute-phase proteins in the immune system and have been hypothesized to be involved in …

Binocular competition is thought to drive eye-specific segregation in the developing visual
system, potentially through Hebbian synaptic learning rules that are sensitive to correlations …