Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune
system attacks its own tissues and organs. However, the causes of SLE remain unknown …

The T cell receptor is a multi-subunit complex that carries out a range of recognition tasks for
multiple lymphocyte types and translates recognition into signals that regulate survival …

Monogenic forms of common variable immunodeficiency and impl... : Current Opinion in Allergy
and Clinical Immunology Monogenic forms of common variable immunodeficiency and …

Developing nanocarriers that can carry medications directly to tumors is an exciting
development in cancer nanomedicine. The efficacy of this intriguing therapeutic approach is …

CTLA4-deficient patients exhibit profound humoral immune dysfunction, yet the basis for the
B cell defect is not known. We observed a marked reduction in transitional to follicular B cell …

In addition to cross-presentation, cross-dressing plays an important role in the induction of
CD8+ T cell immunity. In the process of cross-dressing, conventional dendritic cells (DCs) …

We recently demonstrated that the inhibitory receptor T cell immunoreceptor with Ig and ITIM
domains (TIGIT) assembles in nanoscale clusters at the T cell surface upon ligation with its …

Despite advances in transplantation techniques and immunosuppressive therapies, graft-
versus-host disease (GVHD) remains a significant cause of morbidity and mortality …

Cell-cell communication is critical for the development and function of multicellular
organisms. A crucial means by which cells communicate with one another is physical …

Trogocytosis, an active cellular process involving the transfer of plasma membrane and
attached cytosol during cell-to-cell contact, has been observed prominently in CD4 T cells …