[HTML][HTML] RNA binding proteins (RBPs) and their role in DNA damage and radiation response in cancer

M Mehta, R Raguraman, R Ramesh… - Advanced drug delivery …, 2022 - Elsevier
Traditionally majority of eukaryotic gene expression is influenced by transcriptional and post-
transcriptional events. Alterations in the expression of proteins that act post-transcriptionally …

Single-cell RNA sequencing reveals cell heterogeneity and transcriptome profile of breast cancer lymph node metastasis

K Xu, R Wang, H Xie, L Hu, C Wang, J Xu, C Zhu, Y Liu… - Oncogenesis, 2021 - nature.com
Molecular mechanisms underlying breast cancer lymph node metastasis remain unclear.
Using single-cell sequencing, we investigated the transcriptome profile of 96,796 single …

RNA-binding proteins: Underestimated contributors in tumorigenesis

Y Zhao, C Mir, Y Garcia-Mayea, R Paciucci… - Seminars in Cancer …, 2022 - Elsevier
Abstract mRNA export, translation, splicing, cleavage or capping determine mRNA stability,
which represents one of the primary aspects regulating gene expression and function. RNA …

Regulation of cold-inducible RNA-binding protein (CIRBP) in response to cellular stresses

M Corre, A Lebreton - Biochimie, 2024 - Elsevier
Abstract Cold-inducible RNA-Binding Protein (CIRBP) is a general stress-response factor in
vertebrates harboring two domains: an RNA-recognition motif and a regulatory domain rich …

Controversial roles of cold‑inducible RNA‑binding protein in human cancer

YM Kim, S Hong - International Journal of Oncology, 2021 - spandidos-publications.com
Cold‑inducible RNA‑binding protein (CIRBP) is a cold‑shock protein comprised of an RNA‑
binding motif that is induced by several stressors, such as cold shock, UV radiation, nutrient …

Cold-induced RNA-binding protein promotes glucose metabolism and reduces apoptosis by increasing AKT phosphorylation in mouse skeletal muscle under acute …

Y Liu, P Liu, Y Hu, Y Cao, J Lu, Y Yang, H Lv… - Frontiers in Molecular …, 2021 - frontiersin.org
The main danger of cold stress to animals in cold regions is systemic metabolic changes
and protein synthesis inhibition. Cold-induced RNA-binding protein is a cold shock protein …

Microcystin-LR-induced interaction between M2 tumor-associated macrophage and colorectal cancer cell promotes colorectal cancer cell migration through regulating …

X Jiang, H Zhang, H Zhang, F Wang, X Wang… - International Journal of …, 2023 - mdpi.com
Microcystin-LR (MC-LR) is a toxic secondary metabolite produced by cyanobacteria that has
been demonstrated to promote colorectal cancer (CRC). However, the mechanism by which …

CIRBP Increases the synthesis and secretion of steroid hormones by in yak granulaso cells

R Zhang, Y Pan, M Wang, J Wang, T Zhang… - The Journal of Steroid …, 2024 - Elsevier
As a regulatory protein that upregulates transcription in response to various stresses, cold-
induced RNA-binding protein (CIRBP) is involved in a variety of physiological pathological …

Data mining identifies novel RNA-binding proteins involved in colon and rectal carcinomas

JM García-Cárdenas, I Armendáriz-Castillo… - Frontiers in Cell and …, 2023 - frontiersin.org
Colorectal adenocarcinoma (COREAD) is the second most deadly cancer and third most
frequently encountered malignancy worldwide. Despite efforts in molecular subtyping and …

Type 2 Cystatins and Their Roles in the Regulation of Human Immune Response and Cancer Progression

Z Zhang, F Zhan - Cancers, 2023 - mdpi.com
Simple Summary Type 2 cystatins are a group of small secreted protease inhibitors that
regulate cysteine protease cathepsins and legumain. These enzymes regulate important …