Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Hypertrophic scarring (HTS) is an aberrant form of wound healing that is associated with
excessive deposition of extracellular matrix and connective tissue at the site of injury. In this …

Microenvironment-responsive hydrogels present high potential in treating refractory wounds
due to their capability of on-demand drug release. In this study, a specially designed …

Pluronic F127 hydrogel biomaterial has garnered considerable attention in wound healing
and repair due to its remarkable properties including temperature sensitivity, injectability …

The occurrence of chronic wounds is a major global health issue. These wounds are difficult
to heal as a result of disordered healing mechanisms. The most common types of chronic …

Infection is a major co-morbidity that contributes to impaired healing in diabetic wounds.
Although impairments in diabetic neutrophils have been blamed for this co-morbidity, what …

Abstract Type 3 Secretion System (T3SS) is a highly conserved virulence structure that plays
an essential role in the pathogenesis of many Gram-negative pathogenic bacteria, including …

Macrophages are the main cells shaping the local microenvironment during wound healing.
As the prime T cells in the skin, γδ T cells participate in regulating microenvironment …

Insufficient bone matrix formation caused by diabetic chronic inflammation can result in bone
nonunion, which is perceived as a worldwide epidemic, with a substantial socioeconomic …

Critical limb ischemia (CLI) is a severe manifestation of peripheral artery disease
characterized by ischemic pain, which is frequently associated with diabetes and non …